The Impact of Pregnancy on Functional Neurological Disorder ( FND )

Fuente: Wiley Open Access
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Auteurs principaux: Alexander Lehn, Ingrid Hoeritzauer, Caoimhe McLoughlin, Jon Stone, Syeda Farah Zahir, Jan Coebergh, Yvonne Leavy, Adam Morton, David Palmer
Format: Artículo Open Access
Publié: Wiley 2025
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author Alexander Lehn
Ingrid Hoeritzauer
Caoimhe McLoughlin
Jon Stone
Syeda Farah Zahir
Jan Coebergh
Yvonne Leavy
Adam Morton
David Palmer
author_facet Alexander Lehn
Ingrid Hoeritzauer
Caoimhe McLoughlin
Jon Stone
Syeda Farah Zahir
Jan Coebergh
Yvonne Leavy
Adam Morton
David Palmer
Alexander Lehn
Ingrid Hoeritzauer
Caoimhe McLoughlin
Jon Stone
Syeda Farah Zahir
Jan Coebergh
Yvonne Leavy
Adam Morton
David Palmer
collection Wiley Open Access
contents The Impact of Pregnancy on Functional Neurological Disorder ( FND ) Alexander Lehn Ingrid Hoeritzauer Caoimhe McLoughlin Jon Stone Syeda Farah Zahir Jan Coebergh Yvonne Leavy Adam Morton David Palmer European Journal of Neurology ABSTRACT Background Functional neurological disorder (FND) commonly affects women of reproductive age, yet little is known about its interaction with pregnancy and childbirth. We aimed to explore FND symptom changes during pregnancy, delivery and the postpartum period and understand women's experiences of care. Methods We conducted a cross‐sectional online survey of women with FND who had experienced pregnancy. The questionnaire was co‐designed with clinicians and individuals with lived experience. Results Of 111 respondents, 61 had experienced pregnancy after FND onset. Among 88 who provided onset data, 24% reported symptom onset during pregnancy, delivery, or postpartum, with 1 in 10 reporting onset specifically during the peripartum period. Seven participants described symptom onset or worsening following neuraxial (epidural/spinal) anaesthesia. On a group level, there was no significant change in FND symptoms across pregnancy phases or postpartum. FND symptoms did not worsen with vaginal delivery versus caesarean section. However, women who experienced hyperemesis gravidarum, daily headaches, or instrumented vaginal delivery were more likely to report FND symptom worsening. Although 35% expressed concern about FND during pregnancy and 13% changed pregnancy plans because of FND, the majority reported no difficulties with infant care or breastfeeding. Most participants (85%) received no FND‐specific advice regarding pregnancy, and health professionals were generally perceived to have limited knowledge of FND. Conclusions While FND symptoms remain stable for most women during pregnancy, a subgroup experiences significant changes or new onset. There is an urgent need for prospective studies and for developing educational resources to guide care in this understudied area. 10.1111/ene.70413 http://creativecommons.org/licenses/by-nc/4.0/
doi_str_mv 10.1111/ene.70413
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institution Wiley Open Access
license_str_mv http://creativecommons.org/licenses/by-nc/4.0/
publishDate 2025
publisher Wiley
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spellingShingle The Impact of Pregnancy on Functional Neurological Disorder ( FND )
Alexander Lehn
Ingrid Hoeritzauer
Caoimhe McLoughlin
Jon Stone
Syeda Farah Zahir
Jan Coebergh
Yvonne Leavy
Adam Morton
David Palmer
European Journal of Neurology
The Impact of Pregnancy on Functional Neurological Disorder ( FND ) Alexander Lehn Ingrid Hoeritzauer Caoimhe McLoughlin Jon Stone Syeda Farah Zahir Jan Coebergh Yvonne Leavy Adam Morton David Palmer European Journal of Neurology ABSTRACT Background Functional neurological disorder (FND) commonly affects women of reproductive age, yet little is known about its interaction with pregnancy and childbirth. We aimed to explore FND symptom changes during pregnancy, delivery and the postpartum period and understand women's experiences of care. Methods We conducted a cross‐sectional online survey of women with FND who had experienced pregnancy. The questionnaire was co‐designed with clinicians and individuals with lived experience. Results Of 111 respondents, 61 had experienced pregnancy after FND onset. Among 88 who provided onset data, 24% reported symptom onset during pregnancy, delivery, or postpartum, with 1 in 10 reporting onset specifically during the peripartum period. Seven participants described symptom onset or worsening following neuraxial (epidural/spinal) anaesthesia. On a group level, there was no significant change in FND symptoms across pregnancy phases or postpartum. FND symptoms did not worsen with vaginal delivery versus caesarean section. However, women who experienced hyperemesis gravidarum, daily headaches, or instrumented vaginal delivery were more likely to report FND symptom worsening. Although 35% expressed concern about FND during pregnancy and 13% changed pregnancy plans because of FND, the majority reported no difficulties with infant care or breastfeeding. Most participants (85%) received no FND‐specific advice regarding pregnancy, and health professionals were generally perceived to have limited knowledge of FND. Conclusions While FND symptoms remain stable for most women during pregnancy, a subgroup experiences significant changes or new onset. There is an urgent need for prospective studies and for developing educational resources to guide care in this understudied area. 10.1111/ene.70413 http://creativecommons.org/licenses/by-nc/4.0/
title The Impact of Pregnancy on Functional Neurological Disorder ( FND )
topic European Journal of Neurology
url https://onlinelibrary.wiley.com/doi/10.1111/ene.70413