The unfolded protein response is a potential therapeutic target in pathogenic fungi
Fuente:
Wiley Open Access
Saved in:
| Main Authors: | Hao Zhou, Jinping Zhang, Rong Wang, Ju Huang, Caiyan Xin, Zhangyong Song |
|---|---|
| Format: | Artículo Open Access |
| Published: |
Wiley
2025
|
| Subjects: | |
| Online Access: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
The structural, functional, and therapeutic potential of metacaspases in fungi and protozoa
by: Ane C. M. Duarte, et al.
Published: (2025)
by: Ane C. M. Duarte, et al.
Published: (2025)
The microbiota–gut–brain axis in Huntington's disease: pathogenic mechanisms and therapeutic targets
by: Millicent N. Ekwudo, et al.
Published: (2024)
by: Millicent N. Ekwudo, et al.
Published: (2024)
HAX1 mediates SARS ‐ CoV ‐2 spike‐triggered unfolded protein response in host cells
by: Fang Zhu, et al.
Published: (2025)
by: Fang Zhu, et al.
Published: (2025)
Privileged proteins with a second residence: dual targeting and conditional re‐routing of mitochondrial proteins
by: Ophry Pines, et al.
Published: (2024)
by: Ophry Pines, et al.
Published: (2024)
Posttranslational modifications of phosphodiesterase type 4 enzymes represent novel points for therapeutic targeting
by: Madihah Hussain, et al.
Published: (2025)
by: Madihah Hussain, et al.
Published: (2025)
ER proteostasis meets mitochondrial function: contact sites as hubs of communication and therapeutic targets
by: Giorgia Maria Renna, et al.
Published: (2026)
by: Giorgia Maria Renna, et al.
Published: (2026)
Redirecting TRIM21 with TRIMTACs for the targeted degradation of multimeric proteins
by: Marc A. Scemama de Gialluly, et al.
Published: (2026)
by: Marc A. Scemama de Gialluly, et al.
Published: (2026)
The contribution of mRNA targeting to spatial protein localization in bacteria
by: Wenkang Shang, et al.
Published: (2024)
by: Wenkang Shang, et al.
Published: (2024)
Cas9 beyond CRISPR – SUMOylation , effector‐like potential and pathogenic adaptation
by: Umut Sahin
Published: (2025)
by: Umut Sahin
Published: (2025)
Countering the effector functions of ESAT‐6 protein in Mycobacterium tuberculosis: strategies for developing antimycobacterial therapeutics
by: Akshay Girish Manikoth, et al.
Published: (2025)
by: Akshay Girish Manikoth, et al.
Published: (2025)
Small heat shock protein Hsp20 contributes to pathogenic development of Ustilago maydis by regulating multiple cellular pathways through its interaction with cytoskeletal proteins
by: Aroni Mitra, et al.
Published: (2025)
by: Aroni Mitra, et al.
Published: (2025)
The role of Annexin A2 in Alzheimer's disease: From cellular functions to therapeutic potential
by: Dongyu Shu, et al.
Published: (2026)
by: Dongyu Shu, et al.
Published: (2026)
Production of functional human potassium channel protein K V 1 .5 in an Escherichia coli ‐based cell‐free protein synthesis system
by: Zitong Zhao, et al.
Published: (2025)
by: Zitong Zhao, et al.
Published: (2025)
The unfolded protein response sensor PERK mediates mechanical stress‐induced maturation of focal adhesion complexes in glioblastoma cells
by: Mohammad Khoonkari, et al.
Published: (2024)
by: Mohammad Khoonkari, et al.
Published: (2024)
What's in a name: the multifaceted function of DNA‐ and RNA‐binding proteins in T cell responses
by: Kaspar Bresser, et al.
Published: (2024)
by: Kaspar Bresser, et al.
Published: (2024)
Regulation of the HMGA2‐SNAI2/CXCR4 axis in atherosclerosis and retinal neovascularization: new therapeutic insights
by: Jianan Li, et al.
Published: (2024)
by: Jianan Li, et al.
Published: (2024)
Phosphorylation of cytosolic hPGK1 affects protein stability and ligand binding: implications for its subcellular targeting in cancer
by: Juan Luis Pacheco‐García, et al.
Published: (2024)
by: Juan Luis Pacheco‐García, et al.
Published: (2024)
Biophysical investigation of the molecular interaction between minichromosome maintenance protein 6 and Bloom syndrome helicase
by: Min June Yang, et al.
Published: (2025)
by: Min June Yang, et al.
Published: (2025)
Decidual protein induced by progesterone enhances HIF ‐1α stability to promote mitophagy and glycolysis
by: Baopeng Tian, et al.
Published: (2026)
by: Baopeng Tian, et al.
Published: (2026)
TbTim20 facilitates protein import at a low membrane potential in trypanosomes lacking the mitochondrial genome
by: Corinne von Känel, et al.
Published: (2025)
by: Corinne von Känel, et al.
Published: (2025)
Conserved structural motifs in PAS , LOV , and CRY proteins regulate circadian rhythms and are therapeutic targets
by: Eric D. Brinckman, et al.
Published: (2026)
by: Eric D. Brinckman, et al.
Published: (2026)
Extracellular vesicles in multiple myeloma: pathogenesis and therapeutic application
by: Chloe Wylie, et al.
Published: (2025)
by: Chloe Wylie, et al.
Published: (2025)
An efficient peptide ligase engineered from a bamboo asparaginyl endopeptidase
by: Xin‐Bo Wang, et al.
Published: (2024)
by: Xin‐Bo Wang, et al.
Published: (2024)
The SARS ‐ CoV ‐2 spike protein interacts with HAX1 to modulate cellular stress responses through activation of the UPR
by: Tony Avril, et al.
Published: (2025)
by: Tony Avril, et al.
Published: (2025)
Previously undescribed effects and mechanisms of STAT 3 in HPV ‐induced DNA re‐replication in response to DNA damage
by: Yiying Song, et al.
Published: (2025)
by: Yiying Song, et al.
Published: (2025)
Multifaceted multivalency with a hub protein
by: Douglas R. Walker, et al.
Published: (2025)
by: Douglas R. Walker, et al.
Published: (2025)
The Z isomer of pyridoxilidenerhodanine 5′‐phosphate is an efficient inhibitor of human pyridoxine 5′‐phosphate oxidase, a crucial enzyme in vitamin B 6 salvage pathway and a potential chemotherapeutic target
by: Claudio Graziani, et al.
Published: (2024)
by: Claudio Graziani, et al.
Published: (2024)
KLF 7 promotes neuroblastoma differentiation through the GTP ase signaling pathway by upregulating neuroblast differentiation‐associated protein AHNAK s and glycerophosphodiesterase GDPD 5
by: Shupei Qiao, et al.
Published: (2024)
by: Shupei Qiao, et al.
Published: (2024)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
by: Ana C. Mendes, et al.
Published: (2025)
by: Ana C. Mendes, et al.
Published: (2025)
Mediator W eb: a protein–protein interaction network database for the RNA polymerase II Mediator complex
by: Sourobh Maji, et al.
Published: (2024)
by: Sourobh Maji, et al.
Published: (2024)
Structural insights into the recognition of the A/T‐rich motif in target gene promoters by the LMX 1a homeobox domain
by: Liqing Lin, et al.
Published: (2024)
by: Liqing Lin, et al.
Published: (2024)
Transfer RNA and small molecule therapeutics for aminoacyl‐tRNA synthetase diseases
by: Tristan N. Samuels, et al.
Published: (2024)
by: Tristan N. Samuels, et al.
Published: (2024)
An adamantane‐based ligand as a novel chemical tool for thermosensory TRPM 8 channel therapeutic modulation
by: Angela Lamberti, et al.
Published: (2025)
by: Angela Lamberti, et al.
Published: (2025)
Pinocembrin alleviates renal ischemia–reperfusion injury/unilateral ureteral obstruction (UUO)‐generated renal fibrosis by targeting the CYP1B1/ROS/MAPK axis
by: Bang‐Hua Zhang, et al.
Published: (2025)
by: Bang‐Hua Zhang, et al.
Published: (2025)
Gαs‐specific structural elements attenuate interactions with regulator of G protein signaling (RGS) proteins
by: Sabreen Higazy‐Mreih, et al.
Published: (2025)
by: Sabreen Higazy‐Mreih, et al.
Published: (2025)
Correction to “The chromatin remodeling protein INO 80 contributes to the removal of H 2 A .Z at the p53‐binding site of the p21 gene in response to doxorubicin”
Published: (2026)
Published: (2026)
Depletion of SASP senescent cardiomyocytes with senolytic drugs confers therapeutic effects in doxorubicin‐related cardiotoxicity
by: Wenzheng Xia, et al.
Published: (2024)
by: Wenzheng Xia, et al.
Published: (2024)
Crystal structure and biophysical characterisation of the enterococcal foldase PpiC , a cross‐opsonic antigen against gram‐positive nosocomial pathogens
by: Valeria Napolitano, et al.
Published: (2025)
by: Valeria Napolitano, et al.
Published: (2025)
ADAM17 and its proteolytic targets in disease pathogenesis
by: Abdulbasit Amin, et al.
Published: (2026)
by: Abdulbasit Amin, et al.
Published: (2026)
Interaction with the cysteine‐free protein HAX1 expands the substrate specificity and function of MIA40 beyond protein oxidation
by: Robin Alexander Rothemann, et al.
Published: (2024)
by: Robin Alexander Rothemann, et al.
Published: (2024)
Similar Items
-
The structural, functional, and therapeutic potential of metacaspases in fungi and protozoa
by: Ane C. M. Duarte, et al.
Published: (2025) -
The microbiota–gut–brain axis in Huntington's disease: pathogenic mechanisms and therapeutic targets
by: Millicent N. Ekwudo, et al.
Published: (2024) -
HAX1 mediates SARS ‐ CoV ‐2 spike‐triggered unfolded protein response in host cells
by: Fang Zhu, et al.
Published: (2025) -
Privileged proteins with a second residence: dual targeting and conditional re‐routing of mitochondrial proteins
by: Ophry Pines, et al.
Published: (2024) -
Posttranslational modifications of phosphodiesterase type 4 enzymes represent novel points for therapeutic targeting
by: Madihah Hussain, et al.
Published: (2025)