Parkinson's Disease and Salivary Issues: A Survey

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Main Authors: Beau D. M. van Dijk, Merel C. Verhoeff, Niels van der Aa, Frank Lobbezoo
Format: Artículo Open Access
Published: Wiley 2026
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author Beau D. M. van Dijk
Merel C. Verhoeff
Niels van der Aa
Frank Lobbezoo
author_facet Beau D. M. van Dijk
Merel C. Verhoeff
Niels van der Aa
Frank Lobbezoo
Beau D. M. van Dijk
Merel C. Verhoeff
Niels van der Aa
Frank Lobbezoo
collection Wiley Open Access
contents Parkinson's Disease and Salivary Issues: A Survey Beau D. M. van Dijk Merel C. Verhoeff Niels van der Aa Frank Lobbezoo Gerodontology ABSTRACT Background Salivary dysfunction, including xerostomia and drooling, is common in Parkinson's disease and further impairs oral health and quality of life, which are already compromised in this population. Their effective management demands deeper insight into the complexity of salivary dysfunction. Objective To examine the occurrence and associations of xerostomia and drooling complaints in individuals with Parkinson's disease. Methods 111 individuals with Parkinson's disease (69.9 ± 7.7 years; 46.8% female) participated in an online survey. The questionnaire used validated scales (e.g., Xerostomia Inventory) and original questions. After descriptive analyses, multiple linear regression analyses identified factors (e.g., severity of motor impairment) associated with severity of xerostomia and drooling. Results Xerostomia (64.9%) and drooling (27.0%) were common, with 18.0% of the individuals experiencing both concurrently. Xerostomia was associated with the presence of jaw symptoms (B = 4.63; 95% CI 1.86–7.40), chewing gum usage (B = 1.27; 95% CI 0.52–2.02), swallowing difficulties (B = 0.41; 95% CI 0.04–0.78) and taste alterations (B = 0.15; 95% CI 0.00–0.30). Drooling was associated with the severity of motor impairment (B = 0.40; 95% CI 0.18–0.60) and with swallowing difficulties (B = 0.64; 95% CI 0.14–1.15). Conclusions Xerostomia and drooling complaints frequently co‐occur in individuals with Parkinson's disease. To prevent further deterioration of the oral health‐related quality of life, a comprehensive evaluation of the underlying aetiology of salivary issues in people with Parkinson's disease is crucial to assist in determining suitable treatment. 10.1111/ger.70049 http://creativecommons.org/licenses/by-nc-nd/4.0/
doi_str_mv 10.1111/ger.70049
format Artículo Open Access
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institution Wiley Open Access
license_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
publishDate 2026
publisher Wiley
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spellingShingle Parkinson's Disease and Salivary Issues: A Survey
Beau D. M. van Dijk
Merel C. Verhoeff
Niels van der Aa
Frank Lobbezoo
Gerodontology
Parkinson's Disease and Salivary Issues: A Survey Beau D. M. van Dijk Merel C. Verhoeff Niels van der Aa Frank Lobbezoo Gerodontology ABSTRACT Background Salivary dysfunction, including xerostomia and drooling, is common in Parkinson's disease and further impairs oral health and quality of life, which are already compromised in this population. Their effective management demands deeper insight into the complexity of salivary dysfunction. Objective To examine the occurrence and associations of xerostomia and drooling complaints in individuals with Parkinson's disease. Methods 111 individuals with Parkinson's disease (69.9 ± 7.7 years; 46.8% female) participated in an online survey. The questionnaire used validated scales (e.g., Xerostomia Inventory) and original questions. After descriptive analyses, multiple linear regression analyses identified factors (e.g., severity of motor impairment) associated with severity of xerostomia and drooling. Results Xerostomia (64.9%) and drooling (27.0%) were common, with 18.0% of the individuals experiencing both concurrently. Xerostomia was associated with the presence of jaw symptoms (B = 4.63; 95% CI 1.86–7.40), chewing gum usage (B = 1.27; 95% CI 0.52–2.02), swallowing difficulties (B = 0.41; 95% CI 0.04–0.78) and taste alterations (B = 0.15; 95% CI 0.00–0.30). Drooling was associated with the severity of motor impairment (B = 0.40; 95% CI 0.18–0.60) and with swallowing difficulties (B = 0.64; 95% CI 0.14–1.15). Conclusions Xerostomia and drooling complaints frequently co‐occur in individuals with Parkinson's disease. To prevent further deterioration of the oral health‐related quality of life, a comprehensive evaluation of the underlying aetiology of salivary issues in people with Parkinson's disease is crucial to assist in determining suitable treatment. 10.1111/ger.70049 http://creativecommons.org/licenses/by-nc-nd/4.0/
title Parkinson's Disease and Salivary Issues: A Survey
topic Gerodontology
url https://onlinelibrary.wiley.com/doi/10.1111/ger.70049