Guardado en:
| Autores principales: | , , , |
|---|---|
| Formato: | Artículo Open Access |
| Publicado: |
Wiley
2025
|
| Materias: | |
| Acceso en línea: | https://acamh.onlinelibrary.wiley.com/doi/10.1111/jcpp.70006 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| _version_ | 1867014994912083968 |
|---|---|
| author | Ryann C. Tansey Marc D. Ferger Hilary A. Marusak Leah M. Mayo |
| author_facet | Ryann C. Tansey Marc D. Ferger Hilary A. Marusak Leah M. Mayo Ryann C. Tansey Marc D. Ferger Hilary A. Marusak Leah M. Mayo |
| collection | Wiley Open Access |
| contents | Research Review: What we have learned about the endocannabinoid system in developmental psychopathology Ryann C. Tansey Marc D. Ferger Hilary A. Marusak Leah M. Mayo Journal of Child Psychology and Psychiatry Background The endocannabinoid (eCB) system, the primary target of cannabis, has gained significant attention as a potential novel therapeutic approach for treating a range of psychiatric disorders characterized by dysregulation of stress, emotion, and social behavior. The use of cannabis itself as a pharmacotherapeutic in children and adolescents is limited due to various constraints, including legal status, stigma, and real or perceived negative side effects. Thus, compounds that target the eCB system without the notable unwanted effects of cannabis may offer a more viable approach for developing populations. Methods In this narrative review, we provide an overview of the eCB system, summarizing its function throughout development and its potential contribution to psychopathology in children and adolescents. We highlight evidence of its behavioral role and the dysregulation of this system in various psychiatric disorders. Finally, we summarize current investigations into pharmacological and nonpharmacological therapeutic interventions designed to target the eCB system. Conclusions The eCB system may offer an innovative target for treatments of various psychiatric disorders in child and adolescent populations. However, more research is needed to understand the nuanced developmental trajectory of this system and to determine whether existing compounds are safe and effective for use in these populations. 10.1111/jcpp.70006 http://creativecommons.org/licenses/by/4.0/ |
| doi_str_mv | 10.1111/jcpp.70006 |
| format | Artículo Open Access |
| id | wiley_oa_10_1111_jcpp_70006 |
| institution | Wiley Open Access |
| license_str_mv | http://creativecommons.org/licenses/by/4.0/ |
| publishDate | 2025 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Research Review: What we have learned about the endocannabinoid system in developmental psychopathology Ryann C. Tansey Marc D. Ferger Hilary A. Marusak Leah M. Mayo Journal of Child Psychology and Psychiatry Research Review: What we have learned about the endocannabinoid system in developmental psychopathology Ryann C. Tansey Marc D. Ferger Hilary A. Marusak Leah M. Mayo Journal of Child Psychology and Psychiatry Background The endocannabinoid (eCB) system, the primary target of cannabis, has gained significant attention as a potential novel therapeutic approach for treating a range of psychiatric disorders characterized by dysregulation of stress, emotion, and social behavior. The use of cannabis itself as a pharmacotherapeutic in children and adolescents is limited due to various constraints, including legal status, stigma, and real or perceived negative side effects. Thus, compounds that target the eCB system without the notable unwanted effects of cannabis may offer a more viable approach for developing populations. Methods In this narrative review, we provide an overview of the eCB system, summarizing its function throughout development and its potential contribution to psychopathology in children and adolescents. We highlight evidence of its behavioral role and the dysregulation of this system in various psychiatric disorders. Finally, we summarize current investigations into pharmacological and nonpharmacological therapeutic interventions designed to target the eCB system. Conclusions The eCB system may offer an innovative target for treatments of various psychiatric disorders in child and adolescent populations. However, more research is needed to understand the nuanced developmental trajectory of this system and to determine whether existing compounds are safe and effective for use in these populations. 10.1111/jcpp.70006 http://creativecommons.org/licenses/by/4.0/ |
| title | Research Review: What we have learned about the endocannabinoid system in developmental psychopathology |
| topic | Journal of Child Psychology and Psychiatry |
| url | https://acamh.onlinelibrary.wiley.com/doi/10.1111/jcpp.70006 |