Imagen de Portada

Over‐expression of N‐acetylaspartate synthase exacerbates pathological energetic deficit and accelerates cognitive decline in the 5xFAD mouse

Fuente: Wiley Open Access

Guardado en:

Detalles Bibliográficos
Autores principales:	Jeremy S. Francis, Quy Nguyen, Vladimir Markov, Paola Leone
Formato:	Artículo Open Access
Publicado:	Wiley 2024
Materias:	Journal of Neurochemistry
Acceso en línea:	Acceder al recurso
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Amyloid pathology mediates the associations between plasma fibrinogen and cognition in non‐demented adults
por: Li‐Yun Ma, et al.
Publicado: (2024)

Mass spectrometry imaging highlights dynamic patterns of lipid co‐expression with Aβ plaques in mouse and human brains
por: Helen Xuexia Huang, et al.
Publicado: (2024)

Elevated serum sodium is linked to increased amyloid‐dependent tau pathology, neurodegeneration, and cognitive impairment in Alzheimer's disease
por: Yu‐Han Chen, et al.
Publicado: (2024)

Higher CSF sTREM2 attenuates APOE ε4 ‐related risk for amyloid pathology in cognitively intact adults: The CABLE study
por: Yong‐Chang Wang, et al.
Publicado: (2024)

CXCR2 immunomodulatory therapy protects against microstructural white matter injury and gait abnormalities but does not mitigate deficits of cognition in a preclinical model of cerebral palsy
por: Yuma Kitase, et al.
Publicado: (2024)

The following article for this Special Issue was previously published and can be found in its respective issue online: “Detection of early Alzheimer’s disease‐like molecular alterations in a mouse model expressing human ApoE4”
Publicado: (2024)

Correction to “Selective loss of basal forebrain cholinergic neurons by 192 IgG ‐saporin is associated with decreased phosphorylation of Ser glycogen synthase kinase‐3β”
Publicado: (2024)

The sphingosine 1‐phosphate analogue, FTY720, modulates the lipidomic signature of the mouse hippocampus
por: Daniela M. Magalhães, et al.
Publicado: (2024)

Altered hippocampal doublecortin expression in Parkinson's disease
por: Evelini Plácido, et al.
Publicado: (2024)

Attenuated responses to attention‐modulating drugs in the neuroligin‐3 R451C mouse model of autism
por: R. Dingwall, et al.
Publicado: (2024)

Combined Neuroprotective Effects of N,N‐Dimethyltryptamine and Ventral Root Reimplantation Following Spinal Root Avulsion in Rats
por: Paola Andrea Caro Aponte, et al.
Publicado: (2026)

Testing cognitive normal for Alzheimer's disease prediction
por: Jie Meng, et al.
Publicado: (2024)

Pharmacological target sites for restoration of age‐associated deficits in NMDA receptor‐mediated norepinephrine release in brain
por: Yousef Aljohani, et al.
Publicado: (2024)

The effects of APOE4 and familial Alzheimer's disease mutations on free fatty acid profiles in mouse brain are age‐ and sex‐dependent
por: Sandra den Hoedt, et al.
Publicado: (2024)

Cdk5 inhibition in the SOD1 G93A transgenic mouse model of amyotrophic lateral sclerosis suppresses neurodegeneration and extends survival
por: Ahwon Kim, et al.
Publicado: (2024)

Fundamental Neurochemistry Review: Sphingolipids and Ceramides in Brain Development
por: Kaviya Chinnappa, et al.
Publicado: (2025)

The activation of inflammatory responses in the brain is potentiated by over‐expressing acetylcholinesterase in myeloid lineage of transgenic mice
por: Yingjie Xia, et al.
Publicado: (2024)

Dysregulation of circadian clock gene expression patterns in a treatment‐resistant animal model of depression
por: Kristoffer Højgaard, et al.
Publicado: (2024)

Different stressors uniquely affect the expression of endocannabinoid‐metabolizing enzymes in the central ring ganglia of Lymnaea stagnalis
por: Veronica Rivi, et al.
Publicado: (2024)

Sex‐dependent differences in the ability of nicotine to modulate discrimination learning and cognitive flexibility in mice
por: Yoshiatsu Aomine, et al.
Publicado: (2024)

Palmitoylation regulates norepinephrine transporter uptake, surface localization, and total expression with pathogenic implications in postural orthostatic tachycardia syndrome
por: Christopher R. Brown, et al.
Publicado: (2024)

Roles of metabotropic signaling of nicotine receptors in the development and maintenance of nicotine reward through regulation of dopamine D 3 receptor expression
por: Dooti Kundu, et al.
Publicado: (2024)

Relaxin family peptide receptor 3 ( RXFP3 ) expressing cells in the zona incerta/lateral hypothalamus augment behavioural arousal
por: Brandon K. Richards, et al.
Publicado: (2024)

The kinase LRRK2 is required for the physiological function and expression of the glial glutamate transporter EAAT2 ( SLC1A2 )
por: Angela Di Iacovo, et al.
Publicado: (2024)

A face‐to‐face comparison of the BBB cell models hCMEC / D3 and hBMEC for their applicability to adenoviral expression of transporters
por: Valerio Taggi, et al.
Publicado: (2024)

Circulating medium‐ and long‐chain acylcarnitines are associated with plasma P‐tau181 in cognitively normal older adults
por: Tahmida Sharmin, et al.
Publicado: (2024)

Exploring the reduction in aquaporin‐4 and increased expression of ciliary neurotrophic factor with the frontal–striatal gliosis induced by chronic high‐fat dietary stress
por: Jing‐Ting Fu, et al.
Publicado: (2024)

Cell type‐specific and subcellular expression of phospholipid phosphatase‐related proteins to modulate lyso‐phosphatidic acid synaptic signaling in the developing and adult CNS
por: Alexandra Polyzou, et al.
Publicado: (2024)

AENK ameliorates cognitive impairment and prevents Tau hyperphosphorylation through inhibiting AEP ‐mediated cleavage of SET in rats with ischemic stroke
por: Yi Liu, et al.
Publicado: (2025)

Neuroscience in China: Domestic and Foreign Experts Working Together
por: Vedrana Montana, et al.
Publicado: (2026)

The following article for this Special Issue was previously published and can be found in its respective issue online: “Long‐term nucleus basalis cholinergic depletion induces attentional deficits and impacts cortical neurons and BDNF levels without affecting the NGF synthesis”
Publicado: (2024)

RETRACTION: The oxysterol 27‐hydroxycholesterol regulates α‐synuclein and tyrosine hydroxylase expression levels in human neuroblastoma cells through modulation of liver X receptors and estrogen receptors–relevance to Parkinson’s disease
Publicado: (2024)

GluN2B ‐Derived Small Interfering Peptide ( GluN2B ‐Sip) Protects Against Sevoflurane‐Induced Neurotoxicity in Developing Rats
por: Kun Zhang, et al.
Publicado: (2025)

Effect of Dietary Ketosis and Nicotinamide Riboside on Hippocampal Krebs Cycle Intermediates and Mitochondrial Energetics in a DNA Repair‐Deficient 3xTg / POLβ +/− Alzheimer Disease Mouse Model
por: Robert Pawlosky, et al.
Publicado: (2025)

Input‐Specific Localization of NMDA Receptor GluN2 Subunits in Thalamocortical Neurons
por: Mackenzie A. Topolski, et al.
Publicado: (2025)

Bioenergetic and excitotoxic determinants of cofilactin rod formation
por: Nguyen Mai, et al.
Publicado: (2024)

Upregulation of FMRP Is Involved in Neuropathic Pain by Regulating GluN2B Activation in Rat Spinal Cord
por: Lei Chen, et al.
Publicado: (2025)

Impact of Glucocorticoid‐Associated Stress‐Like Conditions on Aquaporin‐4 in Cultured Astrocytes and Its Modulation by Adenosine A 2A Receptors
por: Liliana Dias, et al.
Publicado: (2025)

Arrestin‐3 binds parkin and enhances parkin‐dependent mitophagy
por: Chen Zheng, et al.
Publicado: (2024)

Breaking the rules of SLC6 transporters: Export of the human creatine transporter‐1 from the endoplasmic reticulum is supported by its N‐terminus
por: Didem Ün, et al.
Publicado: (2024)