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Auteurs principaux: Jiafang Zhu, Qingqing Cen, Rui Chang, Yue Han, Xiaoxi Lin
Format: Artículo Open Access
Publié: Wiley 2024
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Accès en ligne:https://onlinelibrary.wiley.com/doi/10.1111/jocd.16607
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author Jiafang Zhu
Qingqing Cen
Rui Chang
Yue Han
Xiaoxi Lin
author_facet Jiafang Zhu
Qingqing Cen
Rui Chang
Yue Han
Xiaoxi Lin
Jiafang Zhu
Qingqing Cen
Rui Chang
Yue Han
Xiaoxi Lin
collection Wiley Open Access
contents Patchy Dermal Melanocytosis: Differential Diagnosis and Management Jiafang Zhu Qingqing Cen Rui Chang Yue Han Xiaoxi Lin Journal of Cosmetic Dermatology ABSTRACT Background Nevus of Ito and Mongolian spots are distinct clinical presentations of patchy dermal melanocytosis, characterized by similar dermatological manifestations that can pose diagnostic difficulties for clinicians. Aim This review aims to consolidate current understanding and research advancements on these conditions to facilitate clinical diagnosis, differential diagnosis, and management. Methods A comprehensive search of databases including PubMed and Google Scholar was conducted, along with an analysis of pertinent literature retrieved from reference lists spanning nearly four decades. Results Epidemiological, clinical, and pathological profiles exhibit nuanced differences between the two conditions, with unique expressions under electron microscopy and the regression possibility. It is noteworthy that most Mongolian spots naturally fade with advancing age, in contrast to nevus of Ito, which persist and may potentially evolve into malignant lesions. While picosecond laser treatment has shown greater efficacy than nanosecond lasers, the lower‐energy approach holds particular promise in pediatric cases. The therapeutic landscape for patchy dermal melanocytosis is evolving, shifting from selective photothermal action to photomechanical or subcellular photothermal modalities. Conclusion This review underscores the importance of meticulous clinical assessment and the potential of innovative therapeutic approaches in managing these conditions. 10.1111/jocd.16607 http://creativecommons.org/licenses/by/4.0/
doi_str_mv 10.1111/jocd.16607
format Artículo Open Access
id wiley_oa_10_1111_jocd_16607
institution Wiley Open Access
license_str_mv http://creativecommons.org/licenses/by/4.0/
publishDate 2024
publisher Wiley
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spellingShingle Patchy Dermal Melanocytosis: Differential Diagnosis and Management
Jiafang Zhu
Qingqing Cen
Rui Chang
Yue Han
Xiaoxi Lin
Journal of Cosmetic Dermatology
Patchy Dermal Melanocytosis: Differential Diagnosis and Management Jiafang Zhu Qingqing Cen Rui Chang Yue Han Xiaoxi Lin Journal of Cosmetic Dermatology ABSTRACT Background Nevus of Ito and Mongolian spots are distinct clinical presentations of patchy dermal melanocytosis, characterized by similar dermatological manifestations that can pose diagnostic difficulties for clinicians. Aim This review aims to consolidate current understanding and research advancements on these conditions to facilitate clinical diagnosis, differential diagnosis, and management. Methods A comprehensive search of databases including PubMed and Google Scholar was conducted, along with an analysis of pertinent literature retrieved from reference lists spanning nearly four decades. Results Epidemiological, clinical, and pathological profiles exhibit nuanced differences between the two conditions, with unique expressions under electron microscopy and the regression possibility. It is noteworthy that most Mongolian spots naturally fade with advancing age, in contrast to nevus of Ito, which persist and may potentially evolve into malignant lesions. While picosecond laser treatment has shown greater efficacy than nanosecond lasers, the lower‐energy approach holds particular promise in pediatric cases. The therapeutic landscape for patchy dermal melanocytosis is evolving, shifting from selective photothermal action to photomechanical or subcellular photothermal modalities. Conclusion This review underscores the importance of meticulous clinical assessment and the potential of innovative therapeutic approaches in managing these conditions. 10.1111/jocd.16607 http://creativecommons.org/licenses/by/4.0/
title Patchy Dermal Melanocytosis: Differential Diagnosis and Management
topic Journal of Cosmetic Dermatology
url https://onlinelibrary.wiley.com/doi/10.1111/jocd.16607