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Autores principales: M. Walton‐Clark, V. Travail, T. Sparks, A. Eiras‐Diaz, A. Davenport, A. Holmes, A. Kent, C. Prior, C. Stilwell Breakspear, C. Dye, C. Good, C. Motta, F. Valls Sanchez, F. Pilati, G. McLauchlan, G. Ruiz, I. Brás, J. Scott, K. Clarke, K. Peak, L. Goonan, M. Ots, M. Rossell Garcia, N. Lau, N. Mansbridge, P. Garcia Dominguez, S. Conway, S. Keyte, T. Chapman, T. Conley, V. Black, V. Coates, A. DiBella
Formato: Artículo Open Access
Publicado: Wiley 2025
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Acceso en línea:https://onlinelibrary.wiley.com/doi/10.1111/jsap.13821
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author M. Walton‐Clark
V. Travail
T. Sparks
A. Eiras‐Diaz
A. Davenport
A. Holmes
A. Kent
C. Prior
C. Stilwell Breakspear
C. Dye
C. Good
C. Motta
F. Valls Sanchez
F. Pilati
G. McLauchlan
G. Ruiz
I. Brás
J. Scott
K. Clarke
K. Peak
L. Goonan
M. Ots
M. Rossell Garcia
N. Lau
N. Mansbridge
P. Garcia Dominguez
S. Conway
S. Keyte
T. Chapman
T. Conley
V. Black
V. Coates
A. DiBella
author_facet M. Walton‐Clark
V. Travail
T. Sparks
A. Eiras‐Diaz
A. Davenport
A. Holmes
A. Kent
C. Prior
C. Stilwell Breakspear
C. Dye
C. Good
C. Motta
F. Valls Sanchez
F. Pilati
G. McLauchlan
G. Ruiz
I. Brás
J. Scott
K. Clarke
K. Peak
L. Goonan
M. Ots
M. Rossell Garcia
N. Lau
N. Mansbridge
P. Garcia Dominguez
S. Conway
S. Keyte
T. Chapman
T. Conley
V. Black
V. Coates
A. DiBella
M. Walton‐Clark
V. Travail
T. Sparks
A. Eiras‐Diaz
A. Davenport
A. Holmes
A. Kent
C. Prior
C. Stilwell Breakspear
C. Dye
C. Good
C. Motta
F. Valls Sanchez
F. Pilati
G. McLauchlan
G. Ruiz
I. Brás
J. Scott
K. Clarke
K. Peak
L. Goonan
M. Ots
M. Rossell Garcia
N. Lau
N. Mansbridge
P. Garcia Dominguez
S. Conway
S. Keyte
T. Chapman
T. Conley
V. Black
V. Coates
A. DiBella
collection Wiley Open Access
contents Retrospective analysis of the incidence and clinicopathological findings associated with ammonium urate urolithiasis in dogs with congenital portosystemic shunts: 363 cases (2010‐2023) M. Walton‐Clark V. Travail T. Sparks A. Eiras‐Diaz A. Davenport A. Holmes A. Kent C. Prior C. Stilwell Breakspear C. Dye C. Good C. Motta F. Valls Sanchez F. Pilati G. McLauchlan G. Ruiz I. Brás J. Scott K. Clarke K. Peak L. Goonan M. Ots M. Rossell Garcia N. Lau N. Mansbridge P. Garcia Dominguez S. Conway S. Keyte T. Chapman T. Conley V. Black V. Coates A. DiBella Journal of Small Animal Practice ObjectivesTo assess the incidence and clinical findings associated with the presence of ammonium urate urolithiasis in dogs with congenital portosystemic shunts.Materials and MethodsA retrospective review of dogs diagnosed with extrahepatic portosystemic shunts or intrahepatic portosystemic shunts in 15 referral hospitals between 2010 and 2023. Data including signalment, clinical signs, physical examination findings and clinicopathologic test results at the time of the diagnosis were collected, and the presence of ammonium urate urolithiasis was recorded.ResultsA total of 363 dogs were included. The overall incidence of ammonium urate urolithiasis was 19.3%. Dogs with extrahepatic portosystemic shunts were more likely to have urolithiasis compared to those with intrahepatic portosystemic shunts (32.2% vs. 8.0%). Dogs with urolithiasis were older (median 40 vs. 8 months) and more likely to be neutered males (51.4% vs. 9.8%). Ammonia was significantly lower in dogs with urolithiasis. Dogs with urolithiasis were more likely to have haematuria on dipstick analysis and sediment examination.Clinical SignificanceDogs with extrahepatic portosystemic shunts were more likely to have urolithiasis when compared to dogs with intrahepatic portosystemic shunts. Dogs with higher ammonia levels were less likely to have ammonium urate urolithiasis, and older dogs, neutered males, or those with evidence of haematuria had an increased incidence of urolithiasis. 10.1111/jsap.13821 http://onlinelibrary.wiley.com/termsAndConditions#vor
doi_str_mv 10.1111/jsap.13821
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id wiley_oa_10_1111_jsap_13821
institution Wiley Open Access
license_str_mv http://onlinelibrary.wiley.com/termsAndConditions#vor
publishDate 2025
publisher Wiley
record_format wiley_oa
spellingShingle Retrospective analysis of the incidence and clinicopathological findings associated with ammonium urate urolithiasis in dogs with congenital portosystemic shunts: 363 cases (2010‐2023)
M. Walton‐Clark
V. Travail
T. Sparks
A. Eiras‐Diaz
A. Davenport
A. Holmes
A. Kent
C. Prior
C. Stilwell Breakspear
C. Dye
C. Good
C. Motta
F. Valls Sanchez
F. Pilati
G. McLauchlan
G. Ruiz
I. Brás
J. Scott
K. Clarke
K. Peak
L. Goonan
M. Ots
M. Rossell Garcia
N. Lau
N. Mansbridge
P. Garcia Dominguez
S. Conway
S. Keyte
T. Chapman
T. Conley
V. Black
V. Coates
A. DiBella
Journal of Small Animal Practice
Retrospective analysis of the incidence and clinicopathological findings associated with ammonium urate urolithiasis in dogs with congenital portosystemic shunts: 363 cases (2010‐2023) M. Walton‐Clark V. Travail T. Sparks A. Eiras‐Diaz A. Davenport A. Holmes A. Kent C. Prior C. Stilwell Breakspear C. Dye C. Good C. Motta F. Valls Sanchez F. Pilati G. McLauchlan G. Ruiz I. Brás J. Scott K. Clarke K. Peak L. Goonan M. Ots M. Rossell Garcia N. Lau N. Mansbridge P. Garcia Dominguez S. Conway S. Keyte T. Chapman T. Conley V. Black V. Coates A. DiBella Journal of Small Animal Practice ObjectivesTo assess the incidence and clinical findings associated with the presence of ammonium urate urolithiasis in dogs with congenital portosystemic shunts.Materials and MethodsA retrospective review of dogs diagnosed with extrahepatic portosystemic shunts or intrahepatic portosystemic shunts in 15 referral hospitals between 2010 and 2023. Data including signalment, clinical signs, physical examination findings and clinicopathologic test results at the time of the diagnosis were collected, and the presence of ammonium urate urolithiasis was recorded.ResultsA total of 363 dogs were included. The overall incidence of ammonium urate urolithiasis was 19.3%. Dogs with extrahepatic portosystemic shunts were more likely to have urolithiasis compared to those with intrahepatic portosystemic shunts (32.2% vs. 8.0%). Dogs with urolithiasis were older (median 40 vs. 8 months) and more likely to be neutered males (51.4% vs. 9.8%). Ammonia was significantly lower in dogs with urolithiasis. Dogs with urolithiasis were more likely to have haematuria on dipstick analysis and sediment examination.Clinical SignificanceDogs with extrahepatic portosystemic shunts were more likely to have urolithiasis when compared to dogs with intrahepatic portosystemic shunts. Dogs with higher ammonia levels were less likely to have ammonium urate urolithiasis, and older dogs, neutered males, or those with evidence of haematuria had an increased incidence of urolithiasis. 10.1111/jsap.13821 http://onlinelibrary.wiley.com/termsAndConditions#vor
title Retrospective analysis of the incidence and clinicopathological findings associated with ammonium urate urolithiasis in dogs with congenital portosystemic shunts: 363 cases (2010‐2023)
topic Journal of Small Animal Practice
url https://onlinelibrary.wiley.com/doi/10.1111/jsap.13821