The Value of Urethral Pressure Profile Using Air‐Charged Catheters in the Diagnosis of Female Bladder Neck Obstruction

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Auteurs principaux: Yan Qin, Fei Wang, Chaohua Zhang, Liyang Wu
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Publié: Wiley 2025
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author Yan Qin
Fei Wang
Chaohua Zhang
Liyang Wu
author_facet Yan Qin
Fei Wang
Chaohua Zhang
Liyang Wu
Yan Qin
Fei Wang
Chaohua Zhang
Liyang Wu
collection Wiley Open Access
contents The Value of Urethral Pressure Profile Using Air‐Charged Catheters in the Diagnosis of Female Bladder Neck Obstruction Yan Qin Fei Wang Chaohua Zhang Liyang Wu LUTS: Lower Urinary Tract Symptoms ABSTRACTObjectivesRarely have studies focused on the utilization of urethral pressure profile (UPP) in bladder neck obstruction (BNO). This study aimed to evaluate the parameters of UPP in urodynamic testing (UDS) using air‐charged catheters (ACC) and to investigate the value of UPP as a diagnostic tool for female BNO.Patients and MethodsWe retrospectively collected records of 165 female patients with lower urinary tract symptoms (LUTS) who received UDS at our center from September 2020 to September 2022. The whole patient group was divided into BNO group (n = 92) and non‐BNO group (n = 73). The urodynamic data were evaluated.ResultsThe UPP includes urethral pressures at the bladder neck (b‐UP) and urethral sphincter (s‐UP). The b‐UP was higher in the BNO group than in the non‐BNO group [104.50 (40.50) cmH2O vs. 58.00 (33.50) cmH2O, p < 0.001]. According to multivariable logistic regression analysis, b‐UP and bladder voiding efficiency (BVE) were independently associated with BNO. The area under the curve (AUC) of the b‐UP had the best value for predicting BNO [AUC: 0.878, sensitivity: 88.04%, specificity: 76.71%, 95% confidence interval (CI): 0.819–0.924]; its cut‐off value was 72 cmH2O. Meanwhile, Cohen's kappa was 0.65 (95% CI: 0.537–0.770), indicating that UPP as a diagnostic tool was highly consistent with the video‐urodynamic study (VUDS).ConclusionsUPP by air‐charged urodynamic catheters can show the pressure of the bladder neck, with predictive value for identifying BNO in women. The predictive method based on UPP and pressure‐flow study (PFS) without fluoroscopy will improve the diagnostic accuracy of BNO, which could help urologists in making better clinical decisions. 10.1111/luts.70013 http://onlinelibrary.wiley.com/termsAndConditions#vor
doi_str_mv 10.1111/luts.70013
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institution Wiley Open Access
license_str_mv http://onlinelibrary.wiley.com/termsAndConditions#vor
publishDate 2025
publisher Wiley
record_format wiley_oa
spellingShingle The Value of Urethral Pressure Profile Using Air‐Charged Catheters in the Diagnosis of Female Bladder Neck Obstruction
Yan Qin
Fei Wang
Chaohua Zhang
Liyang Wu
LUTS: Lower Urinary Tract Symptoms
The Value of Urethral Pressure Profile Using Air‐Charged Catheters in the Diagnosis of Female Bladder Neck Obstruction Yan Qin Fei Wang Chaohua Zhang Liyang Wu LUTS: Lower Urinary Tract Symptoms ABSTRACTObjectivesRarely have studies focused on the utilization of urethral pressure profile (UPP) in bladder neck obstruction (BNO). This study aimed to evaluate the parameters of UPP in urodynamic testing (UDS) using air‐charged catheters (ACC) and to investigate the value of UPP as a diagnostic tool for female BNO.Patients and MethodsWe retrospectively collected records of 165 female patients with lower urinary tract symptoms (LUTS) who received UDS at our center from September 2020 to September 2022. The whole patient group was divided into BNO group (n = 92) and non‐BNO group (n = 73). The urodynamic data were evaluated.ResultsThe UPP includes urethral pressures at the bladder neck (b‐UP) and urethral sphincter (s‐UP). The b‐UP was higher in the BNO group than in the non‐BNO group [104.50 (40.50) cmH2O vs. 58.00 (33.50) cmH2O, p < 0.001]. According to multivariable logistic regression analysis, b‐UP and bladder voiding efficiency (BVE) were independently associated with BNO. The area under the curve (AUC) of the b‐UP had the best value for predicting BNO [AUC: 0.878, sensitivity: 88.04%, specificity: 76.71%, 95% confidence interval (CI): 0.819–0.924]; its cut‐off value was 72 cmH2O. Meanwhile, Cohen's kappa was 0.65 (95% CI: 0.537–0.770), indicating that UPP as a diagnostic tool was highly consistent with the video‐urodynamic study (VUDS).ConclusionsUPP by air‐charged urodynamic catheters can show the pressure of the bladder neck, with predictive value for identifying BNO in women. The predictive method based on UPP and pressure‐flow study (PFS) without fluoroscopy will improve the diagnostic accuracy of BNO, which could help urologists in making better clinical decisions. 10.1111/luts.70013 http://onlinelibrary.wiley.com/termsAndConditions#vor
title The Value of Urethral Pressure Profile Using Air‐Charged Catheters in the Diagnosis of Female Bladder Neck Obstruction
topic LUTS: Lower Urinary Tract Symptoms
url https://onlinelibrary.wiley.com/doi/10.1111/luts.70013