Cardiac sarcoidosis with extensive and heterogeneous left ventricular FDG uptake in absence of guidelines indication for an implantable defibrillator: Ventricular tachycardia precipitated by immunosuppressive therapy, should we have done differently?
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Wiley
2024
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| _version_ | 1867009891354279936 |
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| author | Emile Voisine Sylvain Lemay Jonathan Beaudoin Philippe Jacob François Philippon Laurie Marchand Bastien Vallée‐Marcotte Florence Bernier Claudine Laliberté Sophie Fortin Marie‐Ève Komlosy David H. Birnie Mario Sénéchal |
| author_facet | Emile Voisine Sylvain Lemay Jonathan Beaudoin Philippe Jacob François Philippon Laurie Marchand Bastien Vallée‐Marcotte Florence Bernier Claudine Laliberté Sophie Fortin Marie‐Ève Komlosy David H. Birnie Mario Sénéchal Emile Voisine Sylvain Lemay Jonathan Beaudoin Philippe Jacob François Philippon Laurie Marchand Bastien Vallée‐Marcotte Florence Bernier Claudine Laliberté Sophie Fortin Marie‐Ève Komlosy David H. Birnie Mario Sénéchal |
| collection | Wiley Open Access |
| contents | Cardiac sarcoidosis with extensive and heterogeneous left ventricular FDG uptake in absence of guidelines indication for an implantable defibrillator: Ventricular tachycardia precipitated by immunosuppressive therapy, should we have done differently? Emile Voisine Sylvain Lemay Jonathan Beaudoin Philippe Jacob François Philippon Laurie Marchand Bastien Vallée‐Marcotte Florence Bernier Claudine Laliberté Sophie Fortin Marie‐Ève Komlosy David H. Birnie Mario Sénéchal Pacing and Clinical Electrophysiology AbstractA 40‐year‐old man, newly diagnosed with cardiac sarcoidosis (CS) presented with symptomatic ventricular tachycardia three days after starting steroid‐based immunosuppressive therapy (IT). There was no clear guideline indication for implantable cardioverter‐defibrillator (ICD) before the initiation of IT. Shortly after ICD implantation and the initiation of anti‐arrhythmic drugs, recurring ventricular arrhythmias required titration of the anti‐arrhythmic drug therapy. One‐year follow‐up assessment showed no significant arrhythmias and complete PET scan FDG uptake suppression. This case, along with recent publications, suggests transient pro‐arrhythmic effects of steroids in patients with CS, which are not appropriately addressed in the current guidelines. We believe ICD implantation should be considered in clinically manifest CS before initiating IT, particularly in cases with heterogeneous and/or extensive FDG uptake on PET scans. 10.1111/pace.14965 http://creativecommons.org/licenses/by-nc/4.0/ |
| doi_str_mv | 10.1111/pace.14965 |
| format | Artículo Open Access |
| id | wiley_oa_10_1111_pace_14965 |
| institution | Wiley Open Access |
| license_str_mv | http://creativecommons.org/licenses/by-nc/4.0/ |
| publishDate | 2024 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Cardiac sarcoidosis with extensive and heterogeneous left ventricular FDG uptake in absence of guidelines indication for an implantable defibrillator: Ventricular tachycardia precipitated by immunosuppressive therapy, should we have done differently? Emile Voisine Sylvain Lemay Jonathan Beaudoin Philippe Jacob François Philippon Laurie Marchand Bastien Vallée‐Marcotte Florence Bernier Claudine Laliberté Sophie Fortin Marie‐Ève Komlosy David H. Birnie Mario Sénéchal Pacing and Clinical Electrophysiology Cardiac sarcoidosis with extensive and heterogeneous left ventricular FDG uptake in absence of guidelines indication for an implantable defibrillator: Ventricular tachycardia precipitated by immunosuppressive therapy, should we have done differently? Emile Voisine Sylvain Lemay Jonathan Beaudoin Philippe Jacob François Philippon Laurie Marchand Bastien Vallée‐Marcotte Florence Bernier Claudine Laliberté Sophie Fortin Marie‐Ève Komlosy David H. Birnie Mario Sénéchal Pacing and Clinical Electrophysiology AbstractA 40‐year‐old man, newly diagnosed with cardiac sarcoidosis (CS) presented with symptomatic ventricular tachycardia three days after starting steroid‐based immunosuppressive therapy (IT). There was no clear guideline indication for implantable cardioverter‐defibrillator (ICD) before the initiation of IT. Shortly after ICD implantation and the initiation of anti‐arrhythmic drugs, recurring ventricular arrhythmias required titration of the anti‐arrhythmic drug therapy. One‐year follow‐up assessment showed no significant arrhythmias and complete PET scan FDG uptake suppression. This case, along with recent publications, suggests transient pro‐arrhythmic effects of steroids in patients with CS, which are not appropriately addressed in the current guidelines. We believe ICD implantation should be considered in clinically manifest CS before initiating IT, particularly in cases with heterogeneous and/or extensive FDG uptake on PET scans. 10.1111/pace.14965 http://creativecommons.org/licenses/by-nc/4.0/ |
| title | Cardiac sarcoidosis with extensive and heterogeneous left ventricular FDG uptake in absence of guidelines indication for an implantable defibrillator: Ventricular tachycardia precipitated by immunosuppressive therapy, should we have done differently? |
| topic | Pacing and Clinical Electrophysiology |
| url | https://onlinelibrary.wiley.com/doi/10.1111/pace.14965 |