Saved in:
| Main Authors: | , , , , , , , , , , , , , , |
|---|---|
| Format: | Artículo Open Access |
| Published: |
Wiley
2024
|
| Subjects: | |
| Online Access: | https://onlinelibrary.wiley.com/doi/10.1111/pace.14992 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Table of Contents:
- Radiofrequency ablation—Real‐time visualization of lesions and their correlation with underlying parameters Fabian Bahlke Andreas Wachter Nico Erhard Florian Englert Jan Syväri Hannah Krafft Miruna Popa Edison Abdiu Carsten Lennerz Marta Telishevska Sarah Lengauer Tilko Reents Gabriele Hessling Isabel Deisenhofer Felix Bourier Pacing and Clinical Electrophysiology AbstractBackgroundLesion durability and transmurality are crucial for successful radiofrequency (RF) ablation. This study provides a model of real‐time RF lesion visualization and insights into the role of underlying parameters, as local impedance (LI).MethodsA force‐sensing, LI‐sensing catheter was used for lesion creation in an ex vivo model involving cross‐sections of porcine cardiac preparations. During 60 s of RF application, one measurement per second was performed regarding lesion size and available ablation parameters. In total, 1847 measurements from n = 36 lesions were performed. Power (20–50 W) and contact force (1–5 g, 10–15 g, 20–25 g) were systematically alternated.ResultsLesion formation was most prominent in the first seconds of RF application during which nonlinear lesion growth was observed (max. 1.08 mm/s for lesion depth and 2.71 mm/s for lesion diameter). Power levels determined the extent of lesion formation in the early phase. After 20 s, lesion size growth velocity approaches 0.1 mm/s at all power levels. LI changes were also highest in the first seconds (up to – 12 Ω/s) and decreased to less than – 0.1Ω/s after prolonged application.ConclusionLesion formation in irrigated RF ablation is a nonlinear process. Final lesion size resulting from an RF application is mainly influenced by high rates of lesion growth in the first seconds of ablation. LI seems to be a good surrogate for differentiating changes in lesion formation. 10.1111/pace.14992 http://creativecommons.org/licenses/by-nc-nd/4.0/