Salvato in:
| Autori principali: | , , , , , , , , , , , , , , , , |
|---|---|
| Natura: | Artículo Open Access |
| Pubblicazione: |
Wiley
2024
|
| Soggetti: | |
| Accesso online: | https://onlinelibrary.wiley.com/doi/10.1111/php.13935 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
|
| _version_ | 1867008014999879680 |
|---|---|
| author | Aliaksandr V. Mikulich Vitaly Yu. Plavskii Antonina I. Tretyakova Raman K. Nahorny Andrey N. Sobchuk Natalia V. Dudchik Olga A. Emeliyanova Anastasia I. Zhabrouskaya Ludmila G. Plavskaya Tatsiana S. Ananich Olga N. Dudinova Ihar A. Leusenka Sergey V. Yakimchuk Alexei D. Svechko Tran Quoc Tien Quang Cong Tong Thanh Phuong Nguyen |
| author_facet | Aliaksandr V. Mikulich Vitaly Yu. Plavskii Antonina I. Tretyakova Raman K. Nahorny Andrey N. Sobchuk Natalia V. Dudchik Olga A. Emeliyanova Anastasia I. Zhabrouskaya Ludmila G. Plavskaya Tatsiana S. Ananich Olga N. Dudinova Ihar A. Leusenka Sergey V. Yakimchuk Alexei D. Svechko Tran Quoc Tien Quang Cong Tong Thanh Phuong Nguyen Aliaksandr V. Mikulich Vitaly Yu. Plavskii Antonina I. Tretyakova Raman K. Nahorny Andrey N. Sobchuk Natalia V. Dudchik Olga A. Emeliyanova Anastasia I. Zhabrouskaya Ludmila G. Plavskaya Tatsiana S. Ananich Olga N. Dudinova Ihar A. Leusenka Sergey V. Yakimchuk Alexei D. Svechko Tran Quoc Tien Quang Cong Tong Thanh Phuong Nguyen |
| collection | Wiley Open Access |
| contents | Potential of using medicinal plant extracts as photosensitizers for antimicrobial photodynamic therapy Aliaksandr V. Mikulich Vitaly Yu. Plavskii Antonina I. Tretyakova Raman K. Nahorny Andrey N. Sobchuk Natalia V. Dudchik Olga A. Emeliyanova Anastasia I. Zhabrouskaya Ludmila G. Plavskaya Tatsiana S. Ananich Olga N. Dudinova Ihar A. Leusenka Sergey V. Yakimchuk Alexei D. Svechko Tran Quoc Tien Quang Cong Tong Thanh Phuong Nguyen Photochemistry and Photobiology AbstractAntimicrobial photodynamic therapy (APDT) is a promising approach to overcome antimicrobial resistance. However, for widespread implementation of this approach, approved photosensitizers are needed. In this study, we used commercially available preparations (Calendulae officinalis floridis extract, Chamomillae recutitae floridis extract, Achillea millefolii herbae extract; Hypericum perforatum extract; Eucalyptus viminalis folia extract) as photosensitizers for inactivation of gram‐negative (Pseudomonas aeruginosa) and gram‐positive (Staphylococcus aureus) bacteria. Spectral‐luminescent analysis has shown that the major chromophores are of chlorophyll (mainly chlorophyll a and b) and hypericin nature. The extracts are efficient generators of singlet oxygen with quantum yield (γΔ) from 0.40 to 0.64 (reference compound, methylene blue with γΔ = 0.52). In APDT assays, bacteria before irradiation were incubated with extracts for 30 min. After irradiation and 24 h of incubation, colony‐forming units (CFU) were counted. Upon exposure of P. aeruginosa to radiation of 405 nm, 590 nm, and 660 nm at equal energy dose of 30 J/cm2 (irradiance – 100 mW/cm2, exposure time – 5 min), the most pronounced effect is observed with blue light (>3 log10 reduction); in case of S. aureus, the effect is approximately equivalent for light of indicated wavelengths and dose (>4 log10 reduction). 10.1111/php.13935 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| doi_str_mv | 10.1111/php.13935 |
| format | Artículo Open Access |
| id | wiley_oa_10_1111_php_13935 |
| institution | Wiley Open Access |
| license_str_mv | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| publishDate | 2024 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Potential of using medicinal plant extracts as photosensitizers for antimicrobial photodynamic therapy Aliaksandr V. Mikulich Vitaly Yu. Plavskii Antonina I. Tretyakova Raman K. Nahorny Andrey N. Sobchuk Natalia V. Dudchik Olga A. Emeliyanova Anastasia I. Zhabrouskaya Ludmila G. Plavskaya Tatsiana S. Ananich Olga N. Dudinova Ihar A. Leusenka Sergey V. Yakimchuk Alexei D. Svechko Tran Quoc Tien Quang Cong Tong Thanh Phuong Nguyen Photochemistry and Photobiology Potential of using medicinal plant extracts as photosensitizers for antimicrobial photodynamic therapy Aliaksandr V. Mikulich Vitaly Yu. Plavskii Antonina I. Tretyakova Raman K. Nahorny Andrey N. Sobchuk Natalia V. Dudchik Olga A. Emeliyanova Anastasia I. Zhabrouskaya Ludmila G. Plavskaya Tatsiana S. Ananich Olga N. Dudinova Ihar A. Leusenka Sergey V. Yakimchuk Alexei D. Svechko Tran Quoc Tien Quang Cong Tong Thanh Phuong Nguyen Photochemistry and Photobiology AbstractAntimicrobial photodynamic therapy (APDT) is a promising approach to overcome antimicrobial resistance. However, for widespread implementation of this approach, approved photosensitizers are needed. In this study, we used commercially available preparations (Calendulae officinalis floridis extract, Chamomillae recutitae floridis extract, Achillea millefolii herbae extract; Hypericum perforatum extract; Eucalyptus viminalis folia extract) as photosensitizers for inactivation of gram‐negative (Pseudomonas aeruginosa) and gram‐positive (Staphylococcus aureus) bacteria. Spectral‐luminescent analysis has shown that the major chromophores are of chlorophyll (mainly chlorophyll a and b) and hypericin nature. The extracts are efficient generators of singlet oxygen with quantum yield (γΔ) from 0.40 to 0.64 (reference compound, methylene blue with γΔ = 0.52). In APDT assays, bacteria before irradiation were incubated with extracts for 30 min. After irradiation and 24 h of incubation, colony‐forming units (CFU) were counted. Upon exposure of P. aeruginosa to radiation of 405 nm, 590 nm, and 660 nm at equal energy dose of 30 J/cm2 (irradiance – 100 mW/cm2, exposure time – 5 min), the most pronounced effect is observed with blue light (>3 log10 reduction); in case of S. aureus, the effect is approximately equivalent for light of indicated wavelengths and dose (>4 log10 reduction). 10.1111/php.13935 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| title | Potential of using medicinal plant extracts as photosensitizers for antimicrobial photodynamic therapy |
| topic | Photochemistry and Photobiology |
| url | https://onlinelibrary.wiley.com/doi/10.1111/php.13935 |