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| Main Authors: | , , , |
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| Format: | Artículo Open Access |
| Published: |
Wiley
2025
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| Subjects: | |
| Online Access: | https://onlinelibrary.wiley.com/doi/10.1111/php.70017 |
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Table of Contents:
- Photochemical construction of chromanone‐fused estrones using a biphasic tandem rearrangement–cyclization approach Matías I. Quindt Gabriel F. Gola Javier A. Ramirez Sergio M. Bonesi Photochemistry and Photobiology Abstract A facile photochemical preparation of 4‐chromanone fused to estrone has successfully been achieved upon direct irradiation with light of 254 nm under a nitrogen atmosphere employing 3‐(2′‐alkenoyl)estrone and 3‐(2′‐alkenoyl)‐17‐ nor estrone derivatives as optimal substrates. The two‐phase acid‐ and base‐catalyzed method relies upon two consecutive pathways in a one‐pot fashion, involving the photo‐Fries rearrangement reaction and a catalyzed intramolecular oxa ‐Michael addition to afford the desired 4‐chromanone fused products in good yields. 10.1111/php.70017 http://onlinelibrary.wiley.com/termsAndConditions#vor