Salvato in:
| Autori principali: | , , , |
|---|---|
| Natura: | Artículo Open Access |
| Pubblicazione: |
Wiley
2026
|
| Soggetti: | |
| Accesso online: | https://onlinelibrary.wiley.com/doi/10.1111/vec.70082 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
|
| _version_ | 1867005812203847680 |
|---|---|
| author | Sarah E. Carotenuto Gena Broussard Gerad A. Fox William K. Hayes |
| author_facet | Sarah E. Carotenuto Gena Broussard Gerad A. Fox William K. Hayes Sarah E. Carotenuto Gena Broussard Gerad A. Fox William K. Hayes |
| collection | Wiley Open Access |
| contents | A Novel Equine F[abʹ] 2 Veterinary Antivenom for North American Viperid Snake Envenomation Demonstrates Efficacy by Rapid Serum Venom Removal and Improvement in Snakebite Severity Score Sarah E. Carotenuto Gena Broussard Gerad A. Fox William K. Hayes Journal of Veterinary Emergency and Critical Care ABSTRACT Objective To assess the efficacy of a new equine F[abʹ] 2 antivenom (US Department of Agriculture code 6101.05) in removing serum venom and lowering the snakebite severity score (SSS) in animals suffering from naturally occurring viperid envenomation. Design Retrospective study, April 2020 to October 2021. Setting Veterinary hospitals across four North American regions. Animals Twenty‐two dogs, one cat, and one horse. Interventions All patients received the new antivenom intravenously and were assessed for clinical response. Most dogs required one vial for clinical control of signs. Measurements and Main Results Among the dogs and cats with detectable initial serum venom, 94.4% showed a strong response to antivenom administration, with a reduction in serum venom ranging from 94% to >99% at 2 h. Animals that experienced a 90% reduction of serum venom within 2 h greatly exceeded the 0% expected of an ineffective antivenom. The canine and feline SSS improved relative to the initial SSS at 2, 6, and 12 h in 57.9%, 77.8%, and 90.9% of cases, respectively. A favorable reduction in SSS was also appreciated in the single horse in the study. Conclusions In the canine, feline, and equine cases of North American viperid envenomation studied, antivenom 6101.05 adequately removed serum venom and lowered the SSS. 10.1111/vec.70082 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| doi_str_mv | 10.1111/vec.70082 |
| format | Artículo Open Access |
| id | wiley_oa_10_1111_vec_70082 |
| institution | Wiley Open Access |
| license_str_mv | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| publishDate | 2026 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | A Novel Equine F[abʹ] 2 Veterinary Antivenom for North American Viperid Snake Envenomation Demonstrates Efficacy by Rapid Serum Venom Removal and Improvement in Snakebite Severity Score Sarah E. Carotenuto Gena Broussard Gerad A. Fox William K. Hayes Journal of Veterinary Emergency and Critical Care A Novel Equine F[abʹ] 2 Veterinary Antivenom for North American Viperid Snake Envenomation Demonstrates Efficacy by Rapid Serum Venom Removal and Improvement in Snakebite Severity Score Sarah E. Carotenuto Gena Broussard Gerad A. Fox William K. Hayes Journal of Veterinary Emergency and Critical Care ABSTRACT Objective To assess the efficacy of a new equine F[abʹ] 2 antivenom (US Department of Agriculture code 6101.05) in removing serum venom and lowering the snakebite severity score (SSS) in animals suffering from naturally occurring viperid envenomation. Design Retrospective study, April 2020 to October 2021. Setting Veterinary hospitals across four North American regions. Animals Twenty‐two dogs, one cat, and one horse. Interventions All patients received the new antivenom intravenously and were assessed for clinical response. Most dogs required one vial for clinical control of signs. Measurements and Main Results Among the dogs and cats with detectable initial serum venom, 94.4% showed a strong response to antivenom administration, with a reduction in serum venom ranging from 94% to >99% at 2 h. Animals that experienced a 90% reduction of serum venom within 2 h greatly exceeded the 0% expected of an ineffective antivenom. The canine and feline SSS improved relative to the initial SSS at 2, 6, and 12 h in 57.9%, 77.8%, and 90.9% of cases, respectively. A favorable reduction in SSS was also appreciated in the single horse in the study. Conclusions In the canine, feline, and equine cases of North American viperid envenomation studied, antivenom 6101.05 adequately removed serum venom and lowered the SSS. 10.1111/vec.70082 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| title | A Novel Equine F[abʹ] 2 Veterinary Antivenom for North American Viperid Snake Envenomation Demonstrates Efficacy by Rapid Serum Venom Removal and Improvement in Snakebite Severity Score |
| topic | Journal of Veterinary Emergency and Critical Care |
| url | https://onlinelibrary.wiley.com/doi/10.1111/vec.70082 |