Voltammetric determination of droxidopa in the presence of carbidopa using a nanostructured base electrochemical sensor

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Autori principali: Moghaddam, Hadi Mahmoudi, Beitollahi, Hadi, Tajik, Somayeh, Jahani, Shohreh, Khabazzadeh, Hojatollah, Alizadeh, Reza
Natura: Recurso digital
Lingua:inglese
Pubblicazione: Zenodo 2017
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author Moghaddam, Hadi Mahmoudi
Beitollahi, Hadi
Tajik, Somayeh
Jahani, Shohreh
Khabazzadeh, Hojatollah
Alizadeh, Reza
author_facet Moghaddam, Hadi Mahmoudi
Beitollahi, Hadi
Tajik, Somayeh
Jahani, Shohreh
Khabazzadeh, Hojatollah
Alizadeh, Reza
contents A novel carbon paste electrode modified with ZnO nanorods and 2-(4-oxo-3-phenyl-3,4-dihydroquinazolinyl)-N?-phenyl-hydrazinecarbothioamide (2PHCZNCPE) was fabricated and employed to study the electrocatalytic oxidation of droxidopa, using cyclic voltammetry, chronoamperometry and square wave voltammetry as diagnostic techniques. It has been found that the oxidation of droxidopa at the surface of modified electrode occurs at a potential of about 435 mV less positive than that of an unmodified carbon paste electrode. Square wave voltammetry exhibits a linear dynamic range from 7.0 108 to 3.010?4 M and a detection limit of 45.0 nM for droxidopa. Finally this modified electrode was used for simultaneous determination of droxidopa and carbidopa. 2017, Pleiades Publishing, Ltd.
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language eng
publishDate 2017
publisher Zenodo
record_format zenodo
spellingShingle Voltammetric determination of droxidopa in the presence of carbidopa using a nanostructured base electrochemical sensor
Moghaddam, Hadi Mahmoudi
Beitollahi, Hadi
Tajik, Somayeh
Jahani, Shohreh
Khabazzadeh, Hojatollah
Alizadeh, Reza
carbidopa
carbon paste electrode
droxidopa
electrocatalysis
voltammetric analysis
ZnO nanorods
A novel carbon paste electrode modified with ZnO nanorods and 2-(4-oxo-3-phenyl-3,4-dihydroquinazolinyl)-N?-phenyl-hydrazinecarbothioamide (2PHCZNCPE) was fabricated and employed to study the electrocatalytic oxidation of droxidopa, using cyclic voltammetry, chronoamperometry and square wave voltammetry as diagnostic techniques. It has been found that the oxidation of droxidopa at the surface of modified electrode occurs at a potential of about 435 mV less positive than that of an unmodified carbon paste electrode. Square wave voltammetry exhibits a linear dynamic range from 7.0 108 to 3.010?4 M and a detection limit of 45.0 nM for droxidopa. Finally this modified electrode was used for simultaneous determination of droxidopa and carbidopa. 2017, Pleiades Publishing, Ltd.
title Voltammetric determination of droxidopa in the presence of carbidopa using a nanostructured base electrochemical sensor
topic carbidopa
carbon paste electrode
droxidopa
electrocatalysis
voltammetric analysis
ZnO nanorods
url https://doi.org/10.1134/S1023193517050123