RECURRENT CHRONIC BULLOUS DISEASE OF CHILDHOOD IN A MALE CHILD A CASE REPORT
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2026
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| author | Furquana Niaz Zainab Zaidi , Tehreem Aslam , Rimsha Humair , Musfirah Imtiaz , Hiba Anwar , Ahmad Rasheed Fariha Akram and Fatima Aijaz |
| author_facet | Furquana Niaz Zainab Zaidi , Tehreem Aslam , Rimsha Humair , Musfirah Imtiaz , Hiba Anwar , Ahmad Rasheed Fariha Akram and Fatima Aijaz |
| contents | <p>Background: Chronic Bullous Disease of Childhood (CBDC), or Linear IgA bullous disease (LABD), is a rare, autoimmune, non-inherited blistering disease primarily affecting children under fiveyears,often presenting as itchy "string-of-pearls" clusters. It is characterized by recurring, self-limiting eruptions of tense blisters, typically treated with dapsone or topical steroids, and generally has a good prognosis.Chronic Bullous Disease of Childhood (CBDC) is a rare autoimmune blistering disorder characterized by linear deposition of IgA along the dermo-epidermal junction which presents with annular vesiculobullous lesions in children. Case Report:We presented a case of a four-year-old male child who developed recurrent generalized pruritus followed by blistering, over a period of seven months. He was previously treated with intravenous steroids with temporary improvement but relapsed after discontinuationOn examination, generalized itchy, painful, fluid-filled blisters on an erythematous base, arranged in an annular (string of pearls) pattern was observed. The patient was treated with oral dapsone (12.5 mg/day) after testing negative for G6PD deficiency, topical steroids and antihistamines. Marked improvement was seen within two weeks, with complete resolution of lesions with residual hyperpigmentation and no relapse to date.</p> |
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| publishDate | 2026 |
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| spellingShingle | RECURRENT CHRONIC BULLOUS DISEASE OF CHILDHOOD IN A MALE CHILD A CASE REPORT Furquana Niaz Zainab Zaidi , Tehreem Aslam , Rimsha Humair , Musfirah Imtiaz , Hiba Anwar , Ahmad Rasheed Fariha Akram and Fatima Aijaz Autoimmune Bullous Chronic Bullous Disease of Childhood child Dapsone Linear IgA Bullous Disease Vesiculobullous Autoimmune Blistering Disorder <p>Background: Chronic Bullous Disease of Childhood (CBDC), or Linear IgA bullous disease (LABD), is a rare, autoimmune, non-inherited blistering disease primarily affecting children under fiveyears,often presenting as itchy "string-of-pearls" clusters. It is characterized by recurring, self-limiting eruptions of tense blisters, typically treated with dapsone or topical steroids, and generally has a good prognosis.Chronic Bullous Disease of Childhood (CBDC) is a rare autoimmune blistering disorder characterized by linear deposition of IgA along the dermo-epidermal junction which presents with annular vesiculobullous lesions in children. Case Report:We presented a case of a four-year-old male child who developed recurrent generalized pruritus followed by blistering, over a period of seven months. He was previously treated with intravenous steroids with temporary improvement but relapsed after discontinuationOn examination, generalized itchy, painful, fluid-filled blisters on an erythematous base, arranged in an annular (string of pearls) pattern was observed. The patient was treated with oral dapsone (12.5 mg/day) after testing negative for G6PD deficiency, topical steroids and antihistamines. Marked improvement was seen within two weeks, with complete resolution of lesions with residual hyperpigmentation and no relapse to date.</p> |
| title | RECURRENT CHRONIC BULLOUS DISEASE OF CHILDHOOD IN A MALE CHILD A CASE REPORT |
| topic | Autoimmune Bullous Chronic Bullous Disease of Childhood child Dapsone Linear IgA Bullous Disease Vesiculobullous Autoimmune Blistering Disorder |
| url | https://doi.org/10.21474/IJAR01/22959 |