The Exposome: Embracing the Complexity for Discovery in Environmental Health

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Autori principali: Cui, Yuxia, Balshaw, David M., Kwok, Richard K., Thompson, Claudia L., Collman, Gwen W., Birnbaum, Linda S.
Natura: Recurso digital
Pubblicazione: Zenodo 2016
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author Cui, Yuxia
Balshaw, David M.
Kwok, Richard K.
Thompson, Claudia L.
Collman, Gwen W.
Birnbaum, Linda S.
author_facet Cui, Yuxia
Balshaw, David M.
Kwok, Richard K.
Thompson, Claudia L.
Collman, Gwen W.
Birnbaum, Linda S.
contents (Uploaded by Plazi for the Bat Literature Project) Environmental exposures are ubiquitous and play a ­fundamental role in the development of complex human diseases. The exposome, which is defined as the totality of environmental exposures over the life course, allows for systematic evaluation of the relationship between exposures and associated biological consequences, and represents a powerful approach for discovery in environmental health research. However, implementing the exposome concept is challenged by the ability to accurately assess multiple exposures and the ability to integrate information across the exposure–disease continuum. On 14–15 January 2015, the National Institute of Environmental Health Sciences (NIEHS) held the Exposome Workshop where a group of international and U.S. scientists from different disciplines gathered to review the state of the science in research areas related to the exposome and to provide recommendations for incorporating the exposome concept into each research area. To move the field forward, the NIEHS is establishing a Children's Health Exposure Analysis Resource (CHEAR) to provide infrastructure support for access to laboratory and statistical analyses to children's health studies. It is recognized that incorporating the exposome concept into exposure and environmental health research will be a long journey and will require significant collaborative efforts from different scientific d­ isciplines, nations, and stakeholders.
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institution Zenodo
language
publishDate 2016
publisher Zenodo
record_format zenodo
spellingShingle The Exposome: Embracing the Complexity for Discovery in Environmental Health
Cui, Yuxia
Balshaw, David M.
Kwok, Richard K.
Thompson, Claudia L.
Collman, Gwen W.
Birnbaum, Linda S.
Biodiversity
Mammalia
Chiroptera
Chordata
Animalia
bats
bat
(Uploaded by Plazi for the Bat Literature Project) Environmental exposures are ubiquitous and play a ­fundamental role in the development of complex human diseases. The exposome, which is defined as the totality of environmental exposures over the life course, allows for systematic evaluation of the relationship between exposures and associated biological consequences, and represents a powerful approach for discovery in environmental health research. However, implementing the exposome concept is challenged by the ability to accurately assess multiple exposures and the ability to integrate information across the exposure–disease continuum. On 14–15 January 2015, the National Institute of Environmental Health Sciences (NIEHS) held the Exposome Workshop where a group of international and U.S. scientists from different disciplines gathered to review the state of the science in research areas related to the exposome and to provide recommendations for incorporating the exposome concept into each research area. To move the field forward, the NIEHS is establishing a Children's Health Exposure Analysis Resource (CHEAR) to provide infrastructure support for access to laboratory and statistical analyses to children's health studies. It is recognized that incorporating the exposome concept into exposure and environmental health research will be a long journey and will require significant collaborative efforts from different scientific d­ isciplines, nations, and stakeholders.
title The Exposome: Embracing the Complexity for Discovery in Environmental Health
topic Biodiversity
Mammalia
Chiroptera
Chordata
Animalia
bats
bat
url https://doi.org/10.5281/zenodo.13410158