Transmission of Japanese Encephalitis Virus from the Black Flying Fox, Pteropus alecto, to Culex annulirostris Mosquitoes, Despite the Absence of Detectable Viremia

Fuente: Zenodo
Saved in:
Bibliographic Details
Main Authors: Van Den Hurk, Andrew F., Smith, Craig S., Field, Hume E., Smith, Ina L., Northill, Judith A., Taylor, Carmel T., Jansen, Cassie C., Smith, Greg A., Mackenzie, John S.
Format: Recurso digital
Published: Zenodo 2009
Subjects:
Online Access:
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1866901260547915776
author Van Den Hurk, Andrew F.
Smith, Craig S.
Field, Hume E.
Smith, Ina L.
Northill, Judith A.
Taylor, Carmel T.
Jansen, Cassie C.
Smith, Greg A.
Mackenzie, John S.
author_facet Van Den Hurk, Andrew F.
Smith, Craig S.
Field, Hume E.
Smith, Ina L.
Northill, Judith A.
Taylor, Carmel T.
Jansen, Cassie C.
Smith, Greg A.
Mackenzie, John S.
contents (Uploaded by Plazi for the Bat Literature Project) To determine the potential role of flying foxes in transmission cycles of Japanese encephalitis virus (JEV) in Australia, we exposed Pteropus alecto (Megachiroptera: Pteropididae) to JEV via infected Culex annulirostris mosquitoes or inoculation. No flying foxes developed symptoms consistent with JEV infection. Anti-JEV IgG antibodies developed in 6/10 flying foxes exposed to infected Cx. annulirostris and in 5/5 inoculated flying foxes. Low-level viremia was detected by real-time reverse transcriptase polymerase chain reaction in 1/5 inoculated flying foxes and this animal was able to infect recipient mosquitoes. Although viremia was not detected in any of the 10 flying foxes that were exposed to JEV by mosquito bite, two animals infected recipient mosquitoes. Likewise, an inoculated flying fox without detectable viremia infected recipient mosquitoes. Although infection rates in recipient mosquitoes were low, the high population densities in roosting camps, coupled with migratory behavior indicate that flying foxes could play a role in the dispersal of JEV.
format Recurso digital
id zenodo_https___doi_org_10_5281_zenodo_13489302
institution Zenodo
language
publishDate 2009
publisher Zenodo
record_format zenodo
spellingShingle Transmission of Japanese Encephalitis Virus from the Black Flying Fox, Pteropus alecto, to Culex annulirostris Mosquitoes, Despite the Absence of Detectable Viremia
Van Den Hurk, Andrew F.
Smith, Craig S.
Field, Hume E.
Smith, Ina L.
Northill, Judith A.
Taylor, Carmel T.
Jansen, Cassie C.
Smith, Greg A.
Mackenzie, John S.
Biodiversity
Mammalia
Chiroptera
Chordata
Animalia
bats
bat
(Uploaded by Plazi for the Bat Literature Project) To determine the potential role of flying foxes in transmission cycles of Japanese encephalitis virus (JEV) in Australia, we exposed Pteropus alecto (Megachiroptera: Pteropididae) to JEV via infected Culex annulirostris mosquitoes or inoculation. No flying foxes developed symptoms consistent with JEV infection. Anti-JEV IgG antibodies developed in 6/10 flying foxes exposed to infected Cx. annulirostris and in 5/5 inoculated flying foxes. Low-level viremia was detected by real-time reverse transcriptase polymerase chain reaction in 1/5 inoculated flying foxes and this animal was able to infect recipient mosquitoes. Although viremia was not detected in any of the 10 flying foxes that were exposed to JEV by mosquito bite, two animals infected recipient mosquitoes. Likewise, an inoculated flying fox without detectable viremia infected recipient mosquitoes. Although infection rates in recipient mosquitoes were low, the high population densities in roosting camps, coupled with migratory behavior indicate that flying foxes could play a role in the dispersal of JEV.
title Transmission of Japanese Encephalitis Virus from the Black Flying Fox, Pteropus alecto, to Culex annulirostris Mosquitoes, Despite the Absence of Detectable Viremia
topic Biodiversity
Mammalia
Chiroptera
Chordata
Animalia
bats
bat
url https://doi.org/10.5281/zenodo.13489302