Trypanosoma Found in Synanthropic Mammals from Urban Forests of Paraná, Southern Brazil

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Hauptverfasser: Drozino, Ricardo Nascimento, Otomura, Flávio Haragushiku, Gazarini, Janaina, Gomes, Mônica Lúcia, Toledo, Max Jean De Ornelas
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Veröffentlicht: Zenodo 2019
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author Drozino, Ricardo Nascimento
Otomura, Flávio Haragushiku
Gazarini, Janaina
Gomes, Mônica Lúcia
Toledo, Max Jean De Ornelas
author_facet Drozino, Ricardo Nascimento
Otomura, Flávio Haragushiku
Gazarini, Janaina
Gomes, Mônica Lúcia
Toledo, Max Jean De Ornelas
contents (Uploaded by Plazi for the Bat Literature Project) Trypanosoma cruzi is a parasitic protozoan that infects a diversity of hosts constituting the cycle of enzootic transmission in wild environments and causing disease in humans (Chagas disease) and domestic animals. Wild mammals constitute natural reservoirs of this parasite, which is transmitted by hematophagous kissing bugs of the family Reduviidae. T. cruzi is genetically subdivided into six discrete typing units (DTUs), T. cruzi (Tc)I to TcVI. In Brazil, especially in the state of Parana´, TcI and TcII are widely distributed. However, TcII is less frequently found in wild reservoirs and triatomine, and more frequently found in patients. The goal of this study was to investigate the natural occurrence of T. cruzi in wild synanthropic mammals captured in urban forest fragments of the Atlantic Forest of Parana´, southern Brazil. In this way, 12 opossums and 35 bats belonging to five species were captured in urban forest parks of the city of Maringa´, Parana´, an area considered endemic for Chagas disease. PCR-kinetoplast DNA molecular diagnostic reveals Trypanosoma sp. infection in 12 (100%) Didelphis albiventris and 10 (40%) Artibeus lituratus. In addition to demonstrating the presence of Trypanosoma in the two groups of mammals studied, we obtained an isolate of the parasite genotyped as TcII by amplification of the cytochrome oxidase II gene by PCR, followed by restriction fragment length polymorphism with AluI, and confirmed by PCR of rDNA 24Sa. This is the first record of the encounter in wild mammals of Trypanosoma DNA (in A. lituratus) and T. cruzi DTU TcII (in D. albiventris) in the state of Parana´.
format Recurso digital
id zenodo_https___doi_org_10_5281_zenodo_13491301
institution Zenodo
language
publishDate 2019
publisher Zenodo
record_format zenodo
spellingShingle Trypanosoma Found in Synanthropic Mammals from Urban Forests of Paraná, Southern Brazil
Drozino, Ricardo Nascimento
Otomura, Flávio Haragushiku
Gazarini, Janaina
Gomes, Mônica Lúcia
Toledo, Max Jean De Ornelas
Biodiversity
Mammalia
Chiroptera
Chordata
Animalia
bats
bat
(Uploaded by Plazi for the Bat Literature Project) Trypanosoma cruzi is a parasitic protozoan that infects a diversity of hosts constituting the cycle of enzootic transmission in wild environments and causing disease in humans (Chagas disease) and domestic animals. Wild mammals constitute natural reservoirs of this parasite, which is transmitted by hematophagous kissing bugs of the family Reduviidae. T. cruzi is genetically subdivided into six discrete typing units (DTUs), T. cruzi (Tc)I to TcVI. In Brazil, especially in the state of Parana´, TcI and TcII are widely distributed. However, TcII is less frequently found in wild reservoirs and triatomine, and more frequently found in patients. The goal of this study was to investigate the natural occurrence of T. cruzi in wild synanthropic mammals captured in urban forest fragments of the Atlantic Forest of Parana´, southern Brazil. In this way, 12 opossums and 35 bats belonging to five species were captured in urban forest parks of the city of Maringa´, Parana´, an area considered endemic for Chagas disease. PCR-kinetoplast DNA molecular diagnostic reveals Trypanosoma sp. infection in 12 (100%) Didelphis albiventris and 10 (40%) Artibeus lituratus. In addition to demonstrating the presence of Trypanosoma in the two groups of mammals studied, we obtained an isolate of the parasite genotyped as TcII by amplification of the cytochrome oxidase II gene by PCR, followed by restriction fragment length polymorphism with AluI, and confirmed by PCR of rDNA 24Sa. This is the first record of the encounter in wild mammals of Trypanosoma DNA (in A. lituratus) and T. cruzi DTU TcII (in D. albiventris) in the state of Parana´.
title Trypanosoma Found in Synanthropic Mammals from Urban Forests of Paraná, Southern Brazil
topic Biodiversity
Mammalia
Chiroptera
Chordata
Animalia
bats
bat
url https://doi.org/10.5281/zenodo.13491301