A Review on Cell and Gene Therapy

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Auteur principal: Radha Virulkar*, Sayali Ganjiwale, Sachin Dighade
Format: Recurso digital
Publié: Zenodo 2025
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author Radha Virulkar*, Sayali Ganjiwale, Sachin Dighade
author_facet Radha Virulkar*, Sayali Ganjiwale, Sachin Dighade
contents <p><span>With the potential to treat a variety of genetic illnesses, malignancies, and chronic aliments, cell and gene therapy (CGT) is a revolutionary method in contemporary medicine. However, because biological materials are complicated, precision is requiring, and many therapies are highly customized, the production of CGT products is fraught with difficulties. This procedure entails the controlled, scalable, and repeatable isolation, alteration, growth, and delivery of cells or gene. Maintaining product quality, making sure regulations are followed, controlling supply chains, and creating economical manufacturing technique are some of the primary obstacles. Although CGT manufacturing has greatly benefited from advancements in bioprocessing automation, quality control, and cryopreservation, the sector still faces challenged in reaching the scalability, consistency, and cost required for broad clinical use. The present state of CGT production, the technologies influencing its future, and the tactics required to get over current obstacles to the effective commercialization of cell and gene therapies</span><span>.</span></p>
format Recurso digital
id zenodo_https___doi_org_10_5281_zenodo_14584479
institution Zenodo
language
publishDate 2025
publisher Zenodo
record_format zenodo
spellingShingle A Review on Cell and Gene Therapy
Radha Virulkar*, Sayali Ganjiwale, Sachin Dighade
Cell therapy, Gene therapy, Viral vector, good manufacturing practices (GMP), Scalability
<p><span>With the potential to treat a variety of genetic illnesses, malignancies, and chronic aliments, cell and gene therapy (CGT) is a revolutionary method in contemporary medicine. However, because biological materials are complicated, precision is requiring, and many therapies are highly customized, the production of CGT products is fraught with difficulties. This procedure entails the controlled, scalable, and repeatable isolation, alteration, growth, and delivery of cells or gene. Maintaining product quality, making sure regulations are followed, controlling supply chains, and creating economical manufacturing technique are some of the primary obstacles. Although CGT manufacturing has greatly benefited from advancements in bioprocessing automation, quality control, and cryopreservation, the sector still faces challenged in reaching the scalability, consistency, and cost required for broad clinical use. The present state of CGT production, the technologies influencing its future, and the tactics required to get over current obstacles to the effective commercialization of cell and gene therapies</span><span>.</span></p>
title A Review on Cell and Gene Therapy
topic Cell therapy, Gene therapy, Viral vector, good manufacturing practices (GMP), Scalability
url https://doi.org/10.5281/zenodo.14584479