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2025
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| Online Access: | https://doi.org/10.5281/zenodo.14587058 |
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| author | Anusha Rani. Y , Aditya. J , Ramya. K , Sireesha. N , Vijaya. T , Venugopal. A , Ankanna. S , Nagalakshmi Devamma. M |
| author_facet | Anusha Rani. Y , Aditya. J , Ramya. K , Sireesha. N , Vijaya. T , Venugopal. A , Ankanna. S , Nagalakshmi Devamma. M |
| contents | <p>Nanotechnology involves the synthesis, characterization, and application of nanoparticles, which range in size <br>from 1 to 99 nm and possess unique properties compared to their bulk counterparts. In this study, a green <br>synthesis approach was employed to fabricate gold nanoparticles (AuNPs) using the extract of dried panicles of <br>Ocimum sanctum (holy basil). The synthesis was confirmed by a color change from yellow to magenta, and UVVis spectroscopy revealed a characteristic peak at 550 nm, indicating successful nanoparticle formation.<br>Characterization techniques highlighted their distinct properties: FTIR spectroscopy identified functional <br>groups responsible for nanoparticle synthesis, dynamic light scattering (DLS) analysis showed a particle size of <br>87.6 nm and a zeta potential of -17.0 mV, suggesting good stability, and SEM analysis revealed a non-uniform <br>surface structure with an average size of 75.6 nm and a spherical shape. The synthesized AuNPs were evaluated <br>for bioactive potential. Although they showed no DPPH free radical scavenging activity, they demonstrated <br>notable antimicrobial activity against Staphylococcus aureus, with a 20 mm zone of inhibition. Furthermore, the <br>nanoparticles exhibited remarkable dye degradation potential, achieving efficiencies of 80.07%, 80.43%, 82.59%, <br>88.15%, and 91.92% at concentrations of 100, 200, 300, 400, and 500 μL, respectively. This study highlights the <br>potential of Ocimum sanctum-derived gold nanoparticles as a sustainable solution for antibacterial and dye <br>degradation applications, showcasing their promise in environmental and biomedical fields</p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_14587058 |
| institution | Zenodo |
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| publishDate | 2025 |
| publisher | Zenodo |
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| spellingShingle | Synthesis, Characterization and Evaluation of Bioactive Potential of Gold Nanoparticles Fabricated Using Ocimum Sanctum Inflorescence Anusha Rani. Y , Aditya. J , Ramya. K , Sireesha. N , Vijaya. T , Venugopal. A , Ankanna. S , Nagalakshmi Devamma. M <p>Nanotechnology involves the synthesis, characterization, and application of nanoparticles, which range in size <br>from 1 to 99 nm and possess unique properties compared to their bulk counterparts. In this study, a green <br>synthesis approach was employed to fabricate gold nanoparticles (AuNPs) using the extract of dried panicles of <br>Ocimum sanctum (holy basil). The synthesis was confirmed by a color change from yellow to magenta, and UVVis spectroscopy revealed a characteristic peak at 550 nm, indicating successful nanoparticle formation.<br>Characterization techniques highlighted their distinct properties: FTIR spectroscopy identified functional <br>groups responsible for nanoparticle synthesis, dynamic light scattering (DLS) analysis showed a particle size of <br>87.6 nm and a zeta potential of -17.0 mV, suggesting good stability, and SEM analysis revealed a non-uniform <br>surface structure with an average size of 75.6 nm and a spherical shape. The synthesized AuNPs were evaluated <br>for bioactive potential. Although they showed no DPPH free radical scavenging activity, they demonstrated <br>notable antimicrobial activity against Staphylococcus aureus, with a 20 mm zone of inhibition. Furthermore, the <br>nanoparticles exhibited remarkable dye degradation potential, achieving efficiencies of 80.07%, 80.43%, 82.59%, <br>88.15%, and 91.92% at concentrations of 100, 200, 300, 400, and 500 μL, respectively. This study highlights the <br>potential of Ocimum sanctum-derived gold nanoparticles as a sustainable solution for antibacterial and dye <br>degradation applications, showcasing their promise in environmental and biomedical fields</p> |
| title | Synthesis, Characterization and Evaluation of Bioactive Potential of Gold Nanoparticles Fabricated Using Ocimum Sanctum Inflorescence |
| url | https://doi.org/10.5281/zenodo.14587058 |