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| Format: | Recurso digital |
| Language: | English |
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2024
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| Online Access: | https://doi.org/10.5281/zenodo.14597802 |
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| author | Parimita Borah Neeraj Sachin Kamboj Surendra Kumar |
| author_facet | Parimita Borah Neeraj Sachin Kamboj Surendra Kumar |
| contents | <p><strong>Introduction:</strong> Modern anesthesia techniques such as laryngoscopy and endotracheal intubation can temporarily elevate hemodynamic parameters such as blood pressure and heart rate in patients with pre-existing cardiovascular or neurological problems by inducing sympathetic activity. <strong>Aim: </strong>The purpose of this study is to determine the reduced cardiovascular changes to laryngoscopy and endotracheal intubation with intravenous Esmolol. <strong>Materials & Methods: </strong>Following approval from the hospital ethical committee and the acquisition of written informed consent from patients, the study included 50 patients with ASA I/II physical status scheduled for surgical procedures. Patients were divided into two groups. Group A (control) received 10 ml of 0.9% normal saline, while group B received 1mg/kg of esmolol intravenously over a period of 2 minutes prior to induction. Patients were monitored using pulse oximetry, NIBP, and ECG. <strong>Results: </strong>The study analyzed the effects of esmolol on heart rate and blood pressure in different groups. The control group A experienced a significant increase in heart rate from laryngoscopy and intubation up to 5 minutes post-intubation, while the B group experienced a decrease before and an increase post-intubation. Systolic blood pressure rose during laryngoscopy and intubation, with significant increases observed at 1, 3, and 5 minutes. Systolic blood pressure decreased in group B, while diastolic blood pressure increased significantly during laryngoscopy and intubation. No discernible changes were observed in systolic blood pressure. <strong>Conclusion: </strong>Esmolol, given two minutes prior to induction, significantly mitigates cardiovascular responses associated with laryngoscopy and intubation.</p> <p> </p> <div> </div> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_14597802 |
| institution | Zenodo |
| language | eng |
| publishDate | 2024 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | Reduced Cardiovascular Changes to Laryngoscopy and Endotracheal Intubation with Intravenous Esmolol Parimita Borah Neeraj Sachin Kamboj Surendra Kumar Intubation, laryngoscopy, esmolol, intravenous, cardiovascular, sympathetic responses <p><strong>Introduction:</strong> Modern anesthesia techniques such as laryngoscopy and endotracheal intubation can temporarily elevate hemodynamic parameters such as blood pressure and heart rate in patients with pre-existing cardiovascular or neurological problems by inducing sympathetic activity. <strong>Aim: </strong>The purpose of this study is to determine the reduced cardiovascular changes to laryngoscopy and endotracheal intubation with intravenous Esmolol. <strong>Materials & Methods: </strong>Following approval from the hospital ethical committee and the acquisition of written informed consent from patients, the study included 50 patients with ASA I/II physical status scheduled for surgical procedures. Patients were divided into two groups. Group A (control) received 10 ml of 0.9% normal saline, while group B received 1mg/kg of esmolol intravenously over a period of 2 minutes prior to induction. Patients were monitored using pulse oximetry, NIBP, and ECG. <strong>Results: </strong>The study analyzed the effects of esmolol on heart rate and blood pressure in different groups. The control group A experienced a significant increase in heart rate from laryngoscopy and intubation up to 5 minutes post-intubation, while the B group experienced a decrease before and an increase post-intubation. Systolic blood pressure rose during laryngoscopy and intubation, with significant increases observed at 1, 3, and 5 minutes. Systolic blood pressure decreased in group B, while diastolic blood pressure increased significantly during laryngoscopy and intubation. No discernible changes were observed in systolic blood pressure. <strong>Conclusion: </strong>Esmolol, given two minutes prior to induction, significantly mitigates cardiovascular responses associated with laryngoscopy and intubation.</p> <p> </p> <div> </div> |
| title | Reduced Cardiovascular Changes to Laryngoscopy and Endotracheal Intubation with Intravenous Esmolol |
| topic | Intubation, laryngoscopy, esmolol, intravenous, cardiovascular, sympathetic responses |
| url | https://doi.org/10.5281/zenodo.14597802 |