Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Recurso digital |
| Language: | English |
| Published: |
Zenodo
2024
|
| Subjects: | |
| Online Access: | https://doi.org/10.5281/zenodo.14597802 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Table of Contents:
- <p><strong>Introduction:</strong> Modern anesthesia techniques such as laryngoscopy and endotracheal intubation can temporarily elevate hemodynamic parameters such as blood pressure and heart rate in patients with pre-existing cardiovascular or neurological problems by inducing sympathetic activity. <strong>Aim: </strong>The purpose of this study is to determine the reduced cardiovascular changes to laryngoscopy and endotracheal intubation with intravenous Esmolol. <strong>Materials & Methods: </strong>Following approval from the hospital ethical committee and the acquisition of written informed consent from patients, the study included 50 patients with ASA I/II physical status scheduled for surgical procedures. Patients were divided into two groups. Group A (control) received 10 ml of 0.9% normal saline, while group B received 1mg/kg of esmolol intravenously over a period of 2 minutes prior to induction. Patients were monitored using pulse oximetry, NIBP, and ECG. <strong>Results: </strong>The study analyzed the effects of esmolol on heart rate and blood pressure in different groups. The control group A experienced a significant increase in heart rate from laryngoscopy and intubation up to 5 minutes post-intubation, while the B group experienced a decrease before and an increase post-intubation. Systolic blood pressure rose during laryngoscopy and intubation, with significant increases observed at 1, 3, and 5 minutes. Systolic blood pressure decreased in group B, while diastolic blood pressure increased significantly during laryngoscopy and intubation. No discernible changes were observed in systolic blood pressure. <strong>Conclusion: </strong>Esmolol, given two minutes prior to induction, significantly mitigates cardiovascular responses associated with laryngoscopy and intubation.</p> <p> </p> <div> </div>