POSSIBILITIES OF DEVELOPING MYELODYSPLASTIC SYNDROME
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2025
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| author | Gadabadze M. Kandashvili T. Sibashvili K. Kacharava G. Gadabadze G. |
| author_facet | Gadabadze M. Kandashvili T. Sibashvili K. Kacharava G. Gadabadze G. |
| contents | <p><span>A rare clinical case report is provided regarding an 83-year-old man who was admitted to the Hematology Department of the First University Clinic of Tbilisi State Medical University (Georgia) in 2021. The patient was scheduled for surgical treatment due to cataract. The patient did not have any symptoms of Fanconi anemia until the age of 80. The preoperative complete blood count revealed leukopenia, neutropenia: leukocyte - 2.6 x 10’9/l; neutrophil - 22%., General condition satisfactory, constitutional type - normosthenic. He does not tolerate alcohol and does not use tobacco. He had no genetic history. There are no developmental defects. This case suggests that myelodysplastic syndrome is multisymptomatic and therefore, determining the underlying causes is crucial. Fanconi anemia, as known, is homozygous, while this case, which has been confirmed as heterozygous, supports the idea that it may transform into myelodysplasia over time. This gives us grounds to conclude that it is advisable to conduct a thorough examination of all cytopenic patients, including from a molecular-genetic perspective.</span></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_14603398 |
| institution | Zenodo |
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| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | POSSIBILITIES OF DEVELOPING MYELODYSPLASTIC SYNDROME Gadabadze M. Kandashvili T. Sibashvili K. Kacharava G. Gadabadze G. Fanconi Anemia, Myelodysplastic Syndrome, Bone Marrow Report. <p><span>A rare clinical case report is provided regarding an 83-year-old man who was admitted to the Hematology Department of the First University Clinic of Tbilisi State Medical University (Georgia) in 2021. The patient was scheduled for surgical treatment due to cataract. The patient did not have any symptoms of Fanconi anemia until the age of 80. The preoperative complete blood count revealed leukopenia, neutropenia: leukocyte - 2.6 x 10’9/l; neutrophil - 22%., General condition satisfactory, constitutional type - normosthenic. He does not tolerate alcohol and does not use tobacco. He had no genetic history. There are no developmental defects. This case suggests that myelodysplastic syndrome is multisymptomatic and therefore, determining the underlying causes is crucial. Fanconi anemia, as known, is homozygous, while this case, which has been confirmed as heterozygous, supports the idea that it may transform into myelodysplasia over time. This gives us grounds to conclude that it is advisable to conduct a thorough examination of all cytopenic patients, including from a molecular-genetic perspective.</span></p> |
| title | POSSIBILITIES OF DEVELOPING MYELODYSPLASTIC SYNDROME |
| topic | Fanconi Anemia, Myelodysplastic Syndrome, Bone Marrow Report. |
| url | https://doi.org/10.5281/zenodo.14603398 |