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| Format: | Recurso digital |
| Language: | English |
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Zenodo
2024
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| Online Access: | https://doi.org/10.5281/zenodo.14605804 |
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| _version_ | 1866901661749870592 |
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| author | Ramesh Kandimalla P. Rajendra Mohammad Sikandar Hari Prasad Reddy Paluru Madhava Rao Veeramalla |
| author_facet | Ramesh Kandimalla P. Rajendra Mohammad Sikandar Hari Prasad Reddy Paluru Madhava Rao Veeramalla |
| contents | <p><strong>Background:</strong> Cognitive decline is a significant public health concern among the elderly, particularly in regions with rapidly aging populations. Cardiometabolic risk factors, including hypertension, diabetes, dyslipidemia, and obesity, have been implicated in the progression of cognitive impairment. However, there is limited data on this association in the South Indian elderly population. <strong>Objective:</strong> This study aims to evaluate the prevalence of cognitive decline among elderly individuals attending MGM Hospital, Warangal, Telangana, India, and to explore its association with cardiometabolic risk factors. <strong>Methods:</strong> A cross-sectional study was conducted among 500 elderly participants (aged ≥60 years) attending outpatient and inpatient services at MGM Hospital, Warangal, Telangana. Cognitive function was assessed using the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA). Cardiometabolic parameters, including blood pressure, fasting blood glucose, lipid profile, and body mass index (BMI), were measured. Demographic, lifestyle, and medical history data were also collected. Logistic regression analysis was performed to identify the independent predictors of cognitive decline. <strong>Results:</strong> The prevalence of cognitive decline was 36%, with higher rates observed in participants aged ≥75 years (52%). Hypertension (p = 0.001), diabetes (p = 0.003), and elevated BMI (p = 0.004) were significantly associated with cognitive decline. Participants with three or more cardiometabolic risk factors were twice as likely to exhibit cognitive impairment compared to those with none (odds ratio [OR]: 2.15; 95% CI: 1.35–3.42). Rural residents and those with lower educational attainment also showed a higher prevalence of cognitive decline. <strong>Conclusion:</strong> This study conducted at MGM Hospital, Warangal, Telangana, highlights a significant association between cognitive decline and cardiometabolic risk factors in the elderly South Indian population. The findings underscore the need for targeted interventions addressing modifiable risk factors such as hypertension, diabetes, and obesity to mitigate cognitive impairment in this vulnerable group. Further longitudinal studies are warranted to establish causality and assess the impact of preventive strategies.</p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_14605804 |
| institution | Zenodo |
| language | eng |
| publishDate | 2024 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | Cognitive Decline and Its Association with Cardiometabolic Risk in the Elderly South Indian Population Ramesh Kandimalla P. Rajendra Mohammad Sikandar Hari Prasad Reddy Paluru Madhava Rao Veeramalla Cognitive Decline, Cardiometabolic Risk, Elderly, South Indian Population, Hypertension, Diabetes, Obesity. <p><strong>Background:</strong> Cognitive decline is a significant public health concern among the elderly, particularly in regions with rapidly aging populations. Cardiometabolic risk factors, including hypertension, diabetes, dyslipidemia, and obesity, have been implicated in the progression of cognitive impairment. However, there is limited data on this association in the South Indian elderly population. <strong>Objective:</strong> This study aims to evaluate the prevalence of cognitive decline among elderly individuals attending MGM Hospital, Warangal, Telangana, India, and to explore its association with cardiometabolic risk factors. <strong>Methods:</strong> A cross-sectional study was conducted among 500 elderly participants (aged ≥60 years) attending outpatient and inpatient services at MGM Hospital, Warangal, Telangana. Cognitive function was assessed using the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA). Cardiometabolic parameters, including blood pressure, fasting blood glucose, lipid profile, and body mass index (BMI), were measured. Demographic, lifestyle, and medical history data were also collected. Logistic regression analysis was performed to identify the independent predictors of cognitive decline. <strong>Results:</strong> The prevalence of cognitive decline was 36%, with higher rates observed in participants aged ≥75 years (52%). Hypertension (p = 0.001), diabetes (p = 0.003), and elevated BMI (p = 0.004) were significantly associated with cognitive decline. Participants with three or more cardiometabolic risk factors were twice as likely to exhibit cognitive impairment compared to those with none (odds ratio [OR]: 2.15; 95% CI: 1.35–3.42). Rural residents and those with lower educational attainment also showed a higher prevalence of cognitive decline. <strong>Conclusion:</strong> This study conducted at MGM Hospital, Warangal, Telangana, highlights a significant association between cognitive decline and cardiometabolic risk factors in the elderly South Indian population. The findings underscore the need for targeted interventions addressing modifiable risk factors such as hypertension, diabetes, and obesity to mitigate cognitive impairment in this vulnerable group. Further longitudinal studies are warranted to establish causality and assess the impact of preventive strategies.</p> |
| title | Cognitive Decline and Its Association with Cardiometabolic Risk in the Elderly South Indian Population |
| topic | Cognitive Decline, Cardiometabolic Risk, Elderly, South Indian Population, Hypertension, Diabetes, Obesity. |
| url | https://doi.org/10.5281/zenodo.14605804 |