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| Auteur principal: | |
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| Format: | Recurso digital |
| Langue: | anglais |
| Publié: |
Zenodo
2006
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| Sujets: | |
| Accès en ligne: | https://doi.org/10.5281/zenodo.14740364 |
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- <p>Non-acute myocardial infarction (MI) is one of the leading causes of chronic heart failure, characterized by the loss of myocardial tissue and the heart's inability to maintain adequate performance. Regenerative medicine has emerged as a promising field for repairing myocardial damage, particularly through the use of stem cells. However, previous approaches have been limited, and many of the treatments under investigation have shown variable results in terms of efficacy and safety. The challenge of this research was to further assess the viability of autologous skeletal myoblast transplantation in patients with non-acute myocardial infarction, building on previous findings (2003) regarding intramyocardial injection of skeletal muscle-derived stem cells. The 2006 study focused on 1-year follow-up to evaluate long-term outcomes, safety, and improvement in cardiac function.</p>