Formulation of Protein-Loaded Nanoparticles via Freeze-Drying

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Main Authors: Durán-Lobato, Matilde, Tovar, Sulay, de Oliveira Diz, Tadeu, Chenlo, Miguel Angel, Alvarez, Clara V, Alonso, Maria Jose
Format: Recurso digital
Language:English
Published: Zenodo 2024
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author Durán-Lobato, Matilde
Tovar, Sulay
de Oliveira Diz, Tadeu
Chenlo, Miguel Angel
Alvarez, Clara V
Alonso, Maria Jose
author_facet Durán-Lobato, Matilde
Tovar, Sulay
de Oliveira Diz, Tadeu
Chenlo, Miguel Angel
Alvarez, Clara V
Alonso, Maria Jose
contents <p>This preprint reports the development of a novel methodology for formulating protein-loaded nanoparticles through freeze-drying. The study highlights the physicochemical properties, stability, and biological performance of insulin-zinc nanocomplexes as a promising oral protein delivery system. This version of the manuscript has not undergone peer review and was later published in <em>Drug Delivery and Translational Research</em> (DOI: <a href="https://doi.org/10.1007/s13346-024-01712-9" target="_new" rel="noopener">10.1007/s13346-024-01712-9</a>).</p>
format Recurso digital
id zenodo_https___doi_org_10_5281_zenodo_14754920
institution Zenodo
language eng
publishDate 2024
publisher Zenodo
record_format zenodo
spellingShingle Formulation of Protein-Loaded Nanoparticles via Freeze-Drying
Durán-Lobato, Matilde
Tovar, Sulay
de Oliveira Diz, Tadeu
Chenlo, Miguel Angel
Alvarez, Clara V
Alonso, Maria Jose
Peptide/protein delivery
Freeze-drying
Administration, Oral
Intestinal Absorption
Nanocomplexes
Nanostructures
<p>This preprint reports the development of a novel methodology for formulating protein-loaded nanoparticles through freeze-drying. The study highlights the physicochemical properties, stability, and biological performance of insulin-zinc nanocomplexes as a promising oral protein delivery system. This version of the manuscript has not undergone peer review and was later published in <em>Drug Delivery and Translational Research</em> (DOI: <a href="https://doi.org/10.1007/s13346-024-01712-9" target="_new" rel="noopener">10.1007/s13346-024-01712-9</a>).</p>
title Formulation of Protein-Loaded Nanoparticles via Freeze-Drying
topic Peptide/protein delivery
Freeze-drying
Administration, Oral
Intestinal Absorption
Nanocomplexes
Nanostructures
url https://doi.org/10.5281/zenodo.14754920