THE BIDIRECTIONAL RELATIONSHIP BETWEEN OBESITY AND HYPERTENSION IN THE PATHOGENESIS OF METABOLIC SYNDROME AND THE IMPACT OF WEIGHT LOSS INTERVENTIONS ON BLOOD PRESSURE REDUCTION
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| Format: | Recurso digital |
| Language: | English |
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Zenodo
2025
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| _version_ | 1866902200851103744 |
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| author | Researcher |
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| contents | <p>Metabolic syndrome (MetS) is a cluster of metabolic abnormalities, including obesity and hypertension, that significantly increase the risk of cardiovascular diseases (CVD). This paper explores the bidirectional relationship between obesity and hypertension in MetS, emphasizing how excess adiposity contributes to increased blood pressure (BP) through multiple pathophysiological mechanisms, including insulin resistance, sympathetic nervous system activation, and vascular dysfunction. Conversely, hypertension exacerbates obesity-related metabolic dysfunction. Recent studies highlight the benefits of weight loss interventions, including diet modifications, exercise, pharmacotherapy, and bariatric surgery, in reducing BP and improving metabolic health. This paper reviews recent literature on the subject and presents data on weight loss interventions and their impact on BP.</p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_14777251 |
| institution | Zenodo |
| language | eng |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | THE BIDIRECTIONAL RELATIONSHIP BETWEEN OBESITY AND HYPERTENSION IN THE PATHOGENESIS OF METABOLIC SYNDROME AND THE IMPACT OF WEIGHT LOSS INTERVENTIONS ON BLOOD PRESSURE REDUCTION Researcher Metabolic Syndrome, Obesity, Hypertension, Weight Loss, Cardiovascular Risk, Insulin Resistance. <p>Metabolic syndrome (MetS) is a cluster of metabolic abnormalities, including obesity and hypertension, that significantly increase the risk of cardiovascular diseases (CVD). This paper explores the bidirectional relationship between obesity and hypertension in MetS, emphasizing how excess adiposity contributes to increased blood pressure (BP) through multiple pathophysiological mechanisms, including insulin resistance, sympathetic nervous system activation, and vascular dysfunction. Conversely, hypertension exacerbates obesity-related metabolic dysfunction. Recent studies highlight the benefits of weight loss interventions, including diet modifications, exercise, pharmacotherapy, and bariatric surgery, in reducing BP and improving metabolic health. This paper reviews recent literature on the subject and presents data on weight loss interventions and their impact on BP.</p> |
| title | THE BIDIRECTIONAL RELATIONSHIP BETWEEN OBESITY AND HYPERTENSION IN THE PATHOGENESIS OF METABOLIC SYNDROME AND THE IMPACT OF WEIGHT LOSS INTERVENTIONS ON BLOOD PRESSURE REDUCTION |
| topic | Metabolic Syndrome, Obesity, Hypertension, Weight Loss, Cardiovascular Risk, Insulin Resistance. |
| url | https://doi.org/10.5281/zenodo.14777251 |