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| Formato: | Recurso digital |
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Zenodo
2025
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| Acceso en línea: | https://doi.org/10.5281/zenodo.14834320 |
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| _version_ | 1866902274243035136 |
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| author | Mamoor, Shahan |
| author_facet | Mamoor, Shahan |
| contents | <p>Axon guidance is a developmental process by which cells of the nervous system position themselves accurately in designed circuitry through the use of repulsive and attractive forces. Molecules that function in axon guidance genes are derived from the semaphorin, ephrin, plexin, netrin, and roundabout (ROBO)/SLIT gene families. We describe here activation and repression of axon guidance genes as cardinal transcriptional features of the breast and lung cancer transcriptome in humans. Expression of some of these genes in the primary tumor was correlated with worse survival outcome. </p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_14834320 |
| institution | Zenodo |
| language | |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | Genes that function in axon guidance are associated with disease progression in breast and lung cancer. Mamoor, Shahan <p>Axon guidance is a developmental process by which cells of the nervous system position themselves accurately in designed circuitry through the use of repulsive and attractive forces. Molecules that function in axon guidance genes are derived from the semaphorin, ephrin, plexin, netrin, and roundabout (ROBO)/SLIT gene families. We describe here activation and repression of axon guidance genes as cardinal transcriptional features of the breast and lung cancer transcriptome in humans. Expression of some of these genes in the primary tumor was correlated with worse survival outcome. </p> |
| title | Genes that function in axon guidance are associated with disease progression in breast and lung cancer. |
| url | https://doi.org/10.5281/zenodo.14834320 |