ABCG2 functions in multi-drug resistance in human cancer in metastasis to the bone.
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| Natura: | Recurso digital |
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2025
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| _version_ | 1866902133278769152 |
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| author | Mamoor, Shahan |
| author_facet | Mamoor, Shahan |
| contents | <p>We describe here a function for the ATP-binding cassette gene ABCG2 in multi-drug resistance in human cancer (1-3), supported by evidence by demonstrating its transcriptional up-regulation with significance at the transcriptome level in metastasis to distant organ sites in human breast cancer (4, 5), and by separate evidence demonstrating that ATP-binding cassette genes function in multi-drug resistance: in resistance to a platinum agent, in resistance to doxorubicin, and in resistance to paclitaxel (2). </p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_14852796 |
| institution | Zenodo |
| language | |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | ABCG2 functions in multi-drug resistance in human cancer in metastasis to the bone. Mamoor, Shahan <p>We describe here a function for the ATP-binding cassette gene ABCG2 in multi-drug resistance in human cancer (1-3), supported by evidence by demonstrating its transcriptional up-regulation with significance at the transcriptome level in metastasis to distant organ sites in human breast cancer (4, 5), and by separate evidence demonstrating that ATP-binding cassette genes function in multi-drug resistance: in resistance to a platinum agent, in resistance to doxorubicin, and in resistance to paclitaxel (2). </p> |
| title | ABCG2 functions in multi-drug resistance in human cancer in metastasis to the bone. |
| url | https://doi.org/10.5281/zenodo.14852796 |