CIRHIS: Cellular Human immune Responses during controlled Human malaria Infection Studies (GHDC-SI-ID-53)
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2025
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| _version_ | 1866902233383174144 |
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| author | Boyle, Michelle Engwerda, Christian Maecker, Holden Obermoser, Gerlinde |
| author_facet | Boyle, Michelle Engwerda, Christian Maecker, Holden Obermoser, Gerlinde |
| contents | <div>The goal of this project is to investigate whether we can use host-directed therapy (ruxolitinib) in conjunction with the anti-malarial drug artemether-lumefantrine to enhance immune responses in malaria-naïve individuals participating in a controlled human malaria infection model with P. falciparum-induced blood-stage malaria.</div> <div>With support from the Gates Foundation’s Collaboratory, we have generated immunoassay data on samples collected from study participants, as well as supernatants obtained from in vitro experiments.</div> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_14861648 |
| institution | Zenodo |
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| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | CIRHIS: Cellular Human immune Responses during controlled Human malaria Infection Studies (GHDC-SI-ID-53) Boyle, Michelle Engwerda, Christian Maecker, Holden Obermoser, Gerlinde Malaria Luminex <div>The goal of this project is to investigate whether we can use host-directed therapy (ruxolitinib) in conjunction with the anti-malarial drug artemether-lumefantrine to enhance immune responses in malaria-naïve individuals participating in a controlled human malaria infection model with P. falciparum-induced blood-stage malaria.</div> <div>With support from the Gates Foundation’s Collaboratory, we have generated immunoassay data on samples collected from study participants, as well as supernatants obtained from in vitro experiments.</div> |
| title | CIRHIS: Cellular Human immune Responses during controlled Human malaria Infection Studies (GHDC-SI-ID-53) |
| topic | Malaria Luminex |
| url | https://doi.org/10.5281/zenodo.14861648 |