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Main Authors: Bumbuc, Roland, Sheraton, Vivek M
Format: Recurso digital
Language:English
Published: Zenodo 2025
Subjects:
Online Access:https://doi.org/10.5281/zenodo.14947764
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author Bumbuc, Roland
Sheraton, Vivek M
author_facet Bumbuc, Roland
Sheraton, Vivek M
contents <p>Burn injuries are marked by a prolonged and intricate inflammatory response that can last for months, making it essential to understand and predict their dynamics to improve treatment strategies and outcomes. CompuCell3D has become an essential tool together with FiPy to model immune responses in the context of burn wound healing. We optimised the parallelization procedure for burn wound immune response simulations. Benchmark and parallelized simulation results provide critical insights into the performance of cc3d simulations for varying endothelial cell counts and processor configurations. We suggest a number of advanced strategies to tackle the challenges highlighted in this study.</p>
format Recurso digital
id zenodo_https___doi_org_10_5281_zenodo_14947764
institution Zenodo
language eng
publishDate 2025
publisher Zenodo
record_format zenodo
spellingShingle Parallel and Optimization Analysis of Spatial Immune Response after Burn Injury simulations
Bumbuc, Roland
Sheraton, Vivek M
Burn wound immune response
Cytokine dynamics
Spatial modeling
Parallel computing
CompuCell3D
FiPy
Agent-based models
Mathematical modeling
Immune system simulation
Partial differential equations
<p>Burn injuries are marked by a prolonged and intricate inflammatory response that can last for months, making it essential to understand and predict their dynamics to improve treatment strategies and outcomes. CompuCell3D has become an essential tool together with FiPy to model immune responses in the context of burn wound healing. We optimised the parallelization procedure for burn wound immune response simulations. Benchmark and parallelized simulation results provide critical insights into the performance of cc3d simulations for varying endothelial cell counts and processor configurations. We suggest a number of advanced strategies to tackle the challenges highlighted in this study.</p>
title Parallel and Optimization Analysis of Spatial Immune Response after Burn Injury simulations
topic Burn wound immune response
Cytokine dynamics
Spatial modeling
Parallel computing
CompuCell3D
FiPy
Agent-based models
Mathematical modeling
Immune system simulation
Partial differential equations
url https://doi.org/10.5281/zenodo.14947764