Design and Synthesis Of Novel Urea / Thiourea Derivatives As Mycobacterium InhA Inhibitors

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Main Authors: INAMDAR KHIJAR MASHAK, SHONE SANTHOSH, SUSHMA
Format: Recurso digital
Published: Zenodo 2025
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author INAMDAR KHIJAR MASHAK
SHONE SANTHOSH
SUSHMA
author_facet INAMDAR KHIJAR MASHAK
SHONE SANTHOSH
SUSHMA
contents <p>Many of the drugs available in the market for the treatment of tuberculosis have developed resistance by Mycobacterium tuberculosis and many nitrogen containing compounds have been reported to posse's relatively high toxicity compared to other derivatives therefore there is a need for the new Antitubercular agents to treat tuberculosis of resistant Mycobacterium tuberculosis infections. Based on the literature survey we planned to synthesize some novel thiourea compounds which are less toxic and more potent anti-tubercular agents.</p>
format Recurso digital
id zenodo_https___doi_org_10_5281_zenodo_15114272
institution Zenodo
language
publishDate 2025
publisher Zenodo
record_format zenodo
spellingShingle Design and Synthesis Of Novel Urea / Thiourea Derivatives As Mycobacterium InhA Inhibitors
INAMDAR KHIJAR MASHAK
SHONE SANTHOSH
SUSHMA
<p>Many of the drugs available in the market for the treatment of tuberculosis have developed resistance by Mycobacterium tuberculosis and many nitrogen containing compounds have been reported to posse's relatively high toxicity compared to other derivatives therefore there is a need for the new Antitubercular agents to treat tuberculosis of resistant Mycobacterium tuberculosis infections. Based on the literature survey we planned to synthesize some novel thiourea compounds which are less toxic and more potent anti-tubercular agents.</p>
title Design and Synthesis Of Novel Urea / Thiourea Derivatives As Mycobacterium InhA Inhibitors
url https://doi.org/10.5281/zenodo.15114272