Saved in:
| Main Author: | |
|---|---|
| Format: | Recurso digital |
| Language: | |
| Published: |
Zenodo
2025
|
| Subjects: | |
| Online Access: | https://doi.org/10.5281/zenodo.15235176 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1866902309470994432 |
|---|---|
| author | CAMBILLAU, Christian |
| author_facet | CAMBILLAU, Christian |
| contents | <p>Type IX secretion system (T9SS) <span> </span>has been studied mainly in Porphyromonas gingivalis. Among the 18 genes, essential for T9SS function, a group of four, porK-L-M-N<span> </span>belongs to a co-transcribed operon that expresses the T9SS core membrane complex. The central component of this complex, PorM (or GldM), is anchored in the inner membrane by a trans-membrane helix and interacts through the outer membrane PorK-N complex. There are available atomic structures</p> <p>PorM complex. Here we report the AlphaFold2 predicted structure of several complexes involving PorK-L-M-N:</p> <ul> <li>A dimer of<span> </span>PorK-PorN</li> <li>A ring of the PorK-PorN complex</li> <li>The PorM dimer in complex with the PorL pentamer,</li> <li>PorK in complex with the PorMd1-3 dimer.</li> </ul> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_15235176 |
| institution | Zenodo |
| language | |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | AlphaFold2 predicted structures of the Porphyromonas gingivalis T9SS components complexes: dimer of PorK-PorN, ring of PorK-PorN, PorM dimer with PorL pentamer, PorK in complex with a dimer of PorM domains 2-4 CAMBILLAU, Christian T9SS, Porphyromonas gingivalis, PorKLMN complex <p>Type IX secretion system (T9SS) <span> </span>has been studied mainly in Porphyromonas gingivalis. Among the 18 genes, essential for T9SS function, a group of four, porK-L-M-N<span> </span>belongs to a co-transcribed operon that expresses the T9SS core membrane complex. The central component of this complex, PorM (or GldM), is anchored in the inner membrane by a trans-membrane helix and interacts through the outer membrane PorK-N complex. There are available atomic structures</p> <p>PorM complex. Here we report the AlphaFold2 predicted structure of several complexes involving PorK-L-M-N:</p> <ul> <li>A dimer of<span> </span>PorK-PorN</li> <li>A ring of the PorK-PorN complex</li> <li>The PorM dimer in complex with the PorL pentamer,</li> <li>PorK in complex with the PorMd1-3 dimer.</li> </ul> |
| title | AlphaFold2 predicted structures of the Porphyromonas gingivalis T9SS components complexes: dimer of PorK-PorN, ring of PorK-PorN, PorM dimer with PorL pentamer, PorK in complex with a dimer of PorM domains 2-4 |
| topic | T9SS, Porphyromonas gingivalis, PorKLMN complex |
| url | https://doi.org/10.5281/zenodo.15235176 |