A REVIEW ON METHOD DEVELOPMENT AND VALIDATION OF STABILITY INDICATING UV METHOD FOR VILDAGLIPTIN
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| Natura: | Recurso digital |
| Lingua: | inglese |
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Zenodo
2025
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| author | Saad Javed Shaikh* Swapnil Daunde |
| author_facet | Saad Javed Shaikh* Swapnil Daunde |
| contents | <p><span lang="EN-US">The present study describes the development of a new rapid, simple, sensitive and reproducible UV Spectrophotometry RP-HPLC, HPTLC method for the analysis of Vildagliptin that offer certain advantages in its simplicity and sensitivity and applicable in routine analysis. Vildagliptin is an antidiabetic agent, belongs to the dipeptidyl peptidase IV (DPP-4) inhibitors. The method employs measurement of absorbance at the wavelength<span> </span>of<span> </span>maximum<span> </span>absorptions<span> </span>of<span> </span>vildagliptin<span> </span>using<span> </span>water<span> </span>as<span> </span>a<span> </span>solven. In order to develop a RP-HPLC, HPTLC, UV effective most of the effect <span>should</span><span> </span><span>be</span><span> </span><span>spent</span><span> </span><span>in</span><span> </span><span>method</span><span> </span><span>development</span><span> </span><span>and</span><span> </span><span>optimization</span><span> </span><span>as</span><span> </span><span>this</span><span> </span><span>will</span><span> </span><span>improve </span>the final method performance. A well- developed method should be easy to validate. Review of literature on drug strongly indicates that there is few <span>methods</span><span> </span><span>available</span><span> </span><span>for</span><span> </span><span>determination</span><span> </span><span>and</span><span> </span><span>validation of</span><span> </span><span>vildagliptin</span><span> </span><span>in</span><span> </span><span>bulk and </span>pharmaceutical dosage forms.</span></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_15302742 |
| institution | Zenodo |
| language | eng |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | A REVIEW ON METHOD DEVELOPMENT AND VALIDATION OF STABILITY INDICATING UV METHOD FOR VILDAGLIPTIN Saad Javed Shaikh* Swapnil Daunde Vildagliptin Antidiabetic Agent Method development UV RP-HPLC Stability Indicating <p><span lang="EN-US">The present study describes the development of a new rapid, simple, sensitive and reproducible UV Spectrophotometry RP-HPLC, HPTLC method for the analysis of Vildagliptin that offer certain advantages in its simplicity and sensitivity and applicable in routine analysis. Vildagliptin is an antidiabetic agent, belongs to the dipeptidyl peptidase IV (DPP-4) inhibitors. The method employs measurement of absorbance at the wavelength<span> </span>of<span> </span>maximum<span> </span>absorptions<span> </span>of<span> </span>vildagliptin<span> </span>using<span> </span>water<span> </span>as<span> </span>a<span> </span>solven. In order to develop a RP-HPLC, HPTLC, UV effective most of the effect <span>should</span><span> </span><span>be</span><span> </span><span>spent</span><span> </span><span>in</span><span> </span><span>method</span><span> </span><span>development</span><span> </span><span>and</span><span> </span><span>optimization</span><span> </span><span>as</span><span> </span><span>this</span><span> </span><span>will</span><span> </span><span>improve </span>the final method performance. A well- developed method should be easy to validate. Review of literature on drug strongly indicates that there is few <span>methods</span><span> </span><span>available</span><span> </span><span>for</span><span> </span><span>determination</span><span> </span><span>and</span><span> </span><span>validation of</span><span> </span><span>vildagliptin</span><span> </span><span>in</span><span> </span><span>bulk and </span>pharmaceutical dosage forms.</span></p> |
| title | A REVIEW ON METHOD DEVELOPMENT AND VALIDATION OF STABILITY INDICATING UV METHOD FOR VILDAGLIPTIN |
| topic | Vildagliptin Antidiabetic Agent Method development UV RP-HPLC Stability Indicating |
| url | https://doi.org/10.5281/zenodo.15302742 |