Evaluation of antimicrobial, antioxidant, antidiabetic activities, and acute toxicity of Elephantopus scaber L.
Fuente:
Zenodo
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Recurso digital |
| Sprache: | Englisch |
| Veröffentlicht: |
Zenodo
2025
|
| Schlagworte: | |
| Online-Zugang: | |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| _version_ | 1866902052289904640 |
|---|---|
| author | Mediterranean Journal of Pharmacy and Pharmaceutical Sciences |
| author_facet | Mediterranean Journal of Pharmacy and Pharmaceutical Sciences |
| contents | <p><em><span>Elephantopus scaber</span></em><span> L., a medicinal plant from Myanmar, was studied to evaluate its biological activity. The activity of antimicrobial assessment showed that ethyl acetate extract exhibited moderate activity in contrast to all six tested organisms. Using the <span>2,2-Diphenyl-1-picrylhydrazyl (</span>DPPH) free radical scavenging assay with ascorbic acid as standard for antioxidant activity showed that ethyl acetate extract possessed 36.28 μg/mL. The <em>in vivo</em> antidiabetic activity with glipizide, as a standard hypoglycemic agent was employed to determine antidiabetic activity. The data parameter under observation for <em>Elephantopus<strong> </strong>scaber</em><strong> </strong>L. reaches its peak at 135 minutes, with a 39.0% reduction.</span><span> No toxic behavior was observed at the limited tested concentrations (2000 mg/kg and 5000 mg/kg) and it suggested a favorable safety profile. </span></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_15365040 |
| institution | Zenodo |
| language | eng |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | Evaluation of antimicrobial, antioxidant, antidiabetic activities, and acute toxicity of Elephantopus scaber L. Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Pharmacy <p><em><span>Elephantopus scaber</span></em><span> L., a medicinal plant from Myanmar, was studied to evaluate its biological activity. The activity of antimicrobial assessment showed that ethyl acetate extract exhibited moderate activity in contrast to all six tested organisms. Using the <span>2,2-Diphenyl-1-picrylhydrazyl (</span>DPPH) free radical scavenging assay with ascorbic acid as standard for antioxidant activity showed that ethyl acetate extract possessed 36.28 μg/mL. The <em>in vivo</em> antidiabetic activity with glipizide, as a standard hypoglycemic agent was employed to determine antidiabetic activity. The data parameter under observation for <em>Elephantopus<strong> </strong>scaber</em><strong> </strong>L. reaches its peak at 135 minutes, with a 39.0% reduction.</span><span> No toxic behavior was observed at the limited tested concentrations (2000 mg/kg and 5000 mg/kg) and it suggested a favorable safety profile. </span></p> |
| title | Evaluation of antimicrobial, antioxidant, antidiabetic activities, and acute toxicity of Elephantopus scaber L. |
| topic | Pharmacy |
| url | https://doi.org/10.5281/zenodo.15365040 |