A Review on Multiple Unit Pellet System (MUPS) Delivery Systems
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2025
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| _version_ | 1866901359713845248 |
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| author | Tushar Tonge*, Shilpa Borkar, Jagdish Baheti |
| author_facet | Tushar Tonge*, Shilpa Borkar, Jagdish Baheti |
| contents | <p><span>The pharmaceutical industry is currently concentrating on creating novel drug delivery systems that improve therapeutic efficacy and lessen adverse effects. When a medication product needs to be administered in a modified release pattern to senior patients, the oral drug delivery system becomes problematic, particularly because they have trouble swallowing. The design of solid dosage forms has made extensive use of Multiple Unit Pellet Systems (MUPS) tablets in recent years. One of the more recent and difficult technologies that combines the benefits of tablets with pellet-filled capsules in a single dose form is the compaction of multiarticulate, also known as the Multiple Unit Pellet System (MUPS). The method of palletization was initially developed in the 1950s, when the first product was released into the market. Multi-unit dose forms have received a lot of attention lately since their smaller particle sizes allow them to pass through the GI tract more readily. When compared to monolithic dose forms, MUPS is thought to have pharmacokinetic benefits. MUPS consistently offers numerous opportunities to create oral formulations with controlled release and delayed release, which aids in the creation of new pharmaceuticals.</span></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_15533086 |
| institution | Zenodo |
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| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | A Review on Multiple Unit Pellet System (MUPS) Delivery Systems Tushar Tonge*, Shilpa Borkar, Jagdish Baheti Pellets, Extrusion-spheronization, Layering Techniques, Spray Pelletization, MUPS, Top – Spraying, Bottom Spray, Top Spray, Tangential Spray <p><span>The pharmaceutical industry is currently concentrating on creating novel drug delivery systems that improve therapeutic efficacy and lessen adverse effects. When a medication product needs to be administered in a modified release pattern to senior patients, the oral drug delivery system becomes problematic, particularly because they have trouble swallowing. The design of solid dosage forms has made extensive use of Multiple Unit Pellet Systems (MUPS) tablets in recent years. One of the more recent and difficult technologies that combines the benefits of tablets with pellet-filled capsules in a single dose form is the compaction of multiarticulate, also known as the Multiple Unit Pellet System (MUPS). The method of palletization was initially developed in the 1950s, when the first product was released into the market. Multi-unit dose forms have received a lot of attention lately since their smaller particle sizes allow them to pass through the GI tract more readily. When compared to monolithic dose forms, MUPS is thought to have pharmacokinetic benefits. MUPS consistently offers numerous opportunities to create oral formulations with controlled release and delayed release, which aids in the creation of new pharmaceuticals.</span></p> |
| title | A Review on Multiple Unit Pellet System (MUPS) Delivery Systems |
| topic | Pellets, Extrusion-spheronization, Layering Techniques, Spray Pelletization, MUPS, Top – Spraying, Bottom Spray, Top Spray, Tangential Spray |
| url | https://doi.org/10.5281/zenodo.15533086 |