| _version_ | 1866902210753855488 |
|---|---|
| author | Suhas Sadaphal*, Suryakant Sapkal**, Jaishree Gawai*** |
| author_facet | Suhas Sadaphal*, Suryakant Sapkal**, Jaishree Gawai*** |
| contents | <p><span>In the current investigation, multicomponent reactions (MCRs) were used to condense a variety of substituted aromatic and heteroaromatic aldehydes with hydroxylamine hydrochloride, and ethyl acetoacetate to provide 3-methyl-4-(hetero)aryl methylene isoxazole-5(4<span>H</span>)-ones derivatives. Under ultrawave sonication, a Tulsion®-8052 MP resin accelerated the process at 45°C. The method outlined has the advantages of being safe, environmentally friendly, and economical because it produces isoxazole derivatives with a yield of 90-96% while removing the need for dangerous solvents.</span></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_15594827 |
| institution | Zenodo |
| language | |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | TULSION®-8052 MP RESIN FOR THE SYNTHESIS OF ISOXAZOL-5 (4H)-ONE DERIVATIVES Suhas Sadaphal*, Suryakant Sapkal**, Jaishree Gawai*** <p><span>In the current investigation, multicomponent reactions (MCRs) were used to condense a variety of substituted aromatic and heteroaromatic aldehydes with hydroxylamine hydrochloride, and ethyl acetoacetate to provide 3-methyl-4-(hetero)aryl methylene isoxazole-5(4<span>H</span>)-ones derivatives. Under ultrawave sonication, a Tulsion®-8052 MP resin accelerated the process at 45°C. The method outlined has the advantages of being safe, environmentally friendly, and economical because it produces isoxazole derivatives with a yield of 90-96% while removing the need for dangerous solvents.</span></p> |
| title | TULSION®-8052 MP RESIN FOR THE SYNTHESIS OF ISOXAZOL-5 (4H)-ONE DERIVATIVES |
| url | https://doi.org/10.5281/zenodo.15594827 |