EXPLORING THE DIVERGENCE OF FUNCTIONAL AND EVOLUTIONAL INTERACTIONS BETWEEN FUNGI AND BACTERIA
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| Natura: | Recurso digital |
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Zenodo
2023
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| _version_ | 1866901043278774272 |
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| author | Abeysinghe, Gayan |
| author_facet | Abeysinghe, Gayan |
| contents | <p>This study investigates bacterial-fungal interaction dynamics through coculturing environmental fungal species with bacterial species. Phenotypic interactions were assessed based on fungal growth, bacterial affinity to hyphae, cell dispersal distance, and motility. The combinations were classified as positive, negative, or neutral. Notably, <em>Aspergillus niger</em>exhibited species-specific antagonism against <em>Bacillus subtilis</em>, linked to the secondary metabolite Pyranonigrin A. Selected pairs underwent LC-MS/MS and transcriptomic analyses to evaluate differential gene expression and metabolite production in coculture versus monoculture. These findings provide ecological and functional insights into microbial network interactions and the potential for unlocking cryptic metabolic pathways.</p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_15668848 |
| institution | Zenodo |
| language | |
| publishDate | 2023 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | EXPLORING THE DIVERGENCE OF FUNCTIONAL AND EVOLUTIONAL INTERACTIONS BETWEEN FUNGI AND BACTERIA Abeysinghe, Gayan <p>This study investigates bacterial-fungal interaction dynamics through coculturing environmental fungal species with bacterial species. Phenotypic interactions were assessed based on fungal growth, bacterial affinity to hyphae, cell dispersal distance, and motility. The combinations were classified as positive, negative, or neutral. Notably, <em>Aspergillus niger</em>exhibited species-specific antagonism against <em>Bacillus subtilis</em>, linked to the secondary metabolite Pyranonigrin A. Selected pairs underwent LC-MS/MS and transcriptomic analyses to evaluate differential gene expression and metabolite production in coculture versus monoculture. These findings provide ecological and functional insights into microbial network interactions and the potential for unlocking cryptic metabolic pathways.</p> |
| title | EXPLORING THE DIVERGENCE OF FUNCTIONAL AND EVOLUTIONAL INTERACTIONS BETWEEN FUNGI AND BACTERIA |
| url | https://doi.org/10.5281/zenodo.15668848 |