Primary Gastrointestinal Non-Hodgkin's Lymphoma Presenting as Pyrexia of Unknown Origin: A Rare Case Report
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| Format: | Recurso digital |
| Language: | English |
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2025
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| _version_ | 1866901589897248768 |
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| author | Dr. Murtaza Makasarwala |
| author_facet | Dr. Murtaza Makasarwala |
| contents | <p><strong><em><span lang="EN-US">Abstract</span></em></strong></p> <p><strong><em><span lang="EN-US">Background: </span></em></strong><em><span lang="EN-US">Primary gastrointestinal non-Hodgkin’s lymphoma (PGINHL) is a rare form of lymphoma that primarily involves the gastrointestinal (GI) tract without systemic lymphadenopathy or bone marrow involvement. It can rarely present as pyrexia of unknown origin (PUO), posing a diagnostic challenge.</span></em></p> <p><strong><em><span lang="EN-US">Case Presentation: </span></em></strong><em><span lang="EN-US">We report a 48-year-old male who presented with PUO and vague lower abdominal discomfort. Imaging revealed aneurysmal dilatation of the distal ileum with perilesional lymphadenopathy. Fine Needle Aspiration Cytology (FNAC) confirmed the diagnosis of lymphoma. The patient underwent surgical resection of the involved bowel segment followed by adjuvant immunochemotherapy using the R-CHOP regimen.</span></em></p> <p><strong><em><span lang="EN-US">Conclusion: </span></em></strong><em><span lang="EN-US">PGINHL should be considered in the differential diagnosis of PUO, particularly in the absence of infectious foci. Surgical resection followed by immunochemotherapy remains the cornerstone of treatment for small bowel PGINHL.</span></em></p> <p><strong><em><span lang="EN-US">Keywords: </span></em></strong><em><span lang="EN-US">Pyrexia of Unknown Origin, Primary Gastrointestinal Lymphoma, DLBCL, Small Bowel Lymphoma, R-CHOP.</span></em></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_15686626 |
| institution | Zenodo |
| language | eng |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | Primary Gastrointestinal Non-Hodgkin's Lymphoma Presenting as Pyrexia of Unknown Origin: A Rare Case Report Dr. Murtaza Makasarwala <p><strong><em><span lang="EN-US">Abstract</span></em></strong></p> <p><strong><em><span lang="EN-US">Background: </span></em></strong><em><span lang="EN-US">Primary gastrointestinal non-Hodgkin’s lymphoma (PGINHL) is a rare form of lymphoma that primarily involves the gastrointestinal (GI) tract without systemic lymphadenopathy or bone marrow involvement. It can rarely present as pyrexia of unknown origin (PUO), posing a diagnostic challenge.</span></em></p> <p><strong><em><span lang="EN-US">Case Presentation: </span></em></strong><em><span lang="EN-US">We report a 48-year-old male who presented with PUO and vague lower abdominal discomfort. Imaging revealed aneurysmal dilatation of the distal ileum with perilesional lymphadenopathy. Fine Needle Aspiration Cytology (FNAC) confirmed the diagnosis of lymphoma. The patient underwent surgical resection of the involved bowel segment followed by adjuvant immunochemotherapy using the R-CHOP regimen.</span></em></p> <p><strong><em><span lang="EN-US">Conclusion: </span></em></strong><em><span lang="EN-US">PGINHL should be considered in the differential diagnosis of PUO, particularly in the absence of infectious foci. Surgical resection followed by immunochemotherapy remains the cornerstone of treatment for small bowel PGINHL.</span></em></p> <p><strong><em><span lang="EN-US">Keywords: </span></em></strong><em><span lang="EN-US">Pyrexia of Unknown Origin, Primary Gastrointestinal Lymphoma, DLBCL, Small Bowel Lymphoma, R-CHOP.</span></em></p> |
| title | Primary Gastrointestinal Non-Hodgkin's Lymphoma Presenting as Pyrexia of Unknown Origin: A Rare Case Report |
| url | https://doi.org/10.5281/zenodo.15686626 |