| _version_ | 1866901719615537152 |
|---|---|
| author | Dr. Rachid Hnini |
| author_facet | Dr. Rachid Hnini |
| contents | <p>By 2050, without joint international action, antibiotic resistance could become one of the leading causes of mortality worldwide, causing up to 10 million deaths each year. It is in this context that the World Health Organization (WHO) has identified antibiotic resistance as one of the most serious threats to global public health. In addition to death and disability, antimicrobial resistance has significant economic costs. The World Bank estimates that antimicrobial resistance could result in US$ 1 trillion additional healthcare costs by 2050, and US$ 1 trillion to US$ 3.4 trillion gross domestic product (GDP) losses per year by 2030. Worldly, Staphylococcus aureus is well-known to be among various pathogenic gram-positive bacteria and it stand out as being responsible for global resistance challenges, significant public health burden, and cost to healthcare. In human as in animal health, Staphylococcus aureus can result in a wide range of diseases, including osteomyelitis, endocarditis, mastitis, thrombophlebitis, meningitis,<br>skin and soft tissue infections, surgical and trauma wound infections, urinary tract infections, gastrointestinal tract infections, pneumonia, toxic shock syndrome, septicaemia, and infections of indwelling medical devices. Earlier, most infections caused by Staphylococcae species can be easily treated with antibiotics; however, in recent years Staphylococcus found its manner to resist the commonly used and effective antibiotics. Nowadays, scientists have warned that the world, in few coming years, will return to a pre-antibiotic age plagued by life-threatening microbial infections on the basis of a recent antibiotic resistance gene database that lists the existence of more than 20,000 antibiotic-resistant genes of 400 types, predicted from available genome sequences. As a consequence of this new challenge, the discovery of novel antimicrobial agents to which microbes cannot develop resistance easily is one of the major medical concerns of the 21st century.</p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_15694740 |
| institution | Zenodo |
| language | |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | In Human and Veterinary Medicine: The Golden Age of Antibiotics is Coming to an End- Case of Staphylococcus aureus Dr. Rachid Hnini <p>By 2050, without joint international action, antibiotic resistance could become one of the leading causes of mortality worldwide, causing up to 10 million deaths each year. It is in this context that the World Health Organization (WHO) has identified antibiotic resistance as one of the most serious threats to global public health. In addition to death and disability, antimicrobial resistance has significant economic costs. The World Bank estimates that antimicrobial resistance could result in US$ 1 trillion additional healthcare costs by 2050, and US$ 1 trillion to US$ 3.4 trillion gross domestic product (GDP) losses per year by 2030. Worldly, Staphylococcus aureus is well-known to be among various pathogenic gram-positive bacteria and it stand out as being responsible for global resistance challenges, significant public health burden, and cost to healthcare. In human as in animal health, Staphylococcus aureus can result in a wide range of diseases, including osteomyelitis, endocarditis, mastitis, thrombophlebitis, meningitis,<br>skin and soft tissue infections, surgical and trauma wound infections, urinary tract infections, gastrointestinal tract infections, pneumonia, toxic shock syndrome, septicaemia, and infections of indwelling medical devices. Earlier, most infections caused by Staphylococcae species can be easily treated with antibiotics; however, in recent years Staphylococcus found its manner to resist the commonly used and effective antibiotics. Nowadays, scientists have warned that the world, in few coming years, will return to a pre-antibiotic age plagued by life-threatening microbial infections on the basis of a recent antibiotic resistance gene database that lists the existence of more than 20,000 antibiotic-resistant genes of 400 types, predicted from available genome sequences. As a consequence of this new challenge, the discovery of novel antimicrobial agents to which microbes cannot develop resistance easily is one of the major medical concerns of the 21st century.</p> |
| title | In Human and Veterinary Medicine: The Golden Age of Antibiotics is Coming to an End- Case of Staphylococcus aureus |
| url | https://doi.org/10.5281/zenodo.15694740 |