Synthesis, Physicochemical Characterization And Biological Activities Of Dapsone Derived Schiff Base Ligand And Their Co(II) Complexes
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| Format: | Recurso digital |
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2023
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| _version_ | 1866902226418532352 |
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| author | Gaikwad, Mrs. Kundalkesha Dharmentra |
| author_facet | Gaikwad, Mrs. Kundalkesha Dharmentra |
| contents | <p><strong><span>Abstract:</span></strong><span> </span></p> <p><span>This work presents the synthesis and characterization of five <a name="_Hlk115000827"></a>diphenylsulphone (Dapsone) derived Schiff base ligands (L<sub>1</sub>- L<sub>5</sub>). Using the aforementioned ligands, Co (II) complexes were synthesized in 1:1 stoichiometric ratio. The synthesized Schiff base and their complexes were characterized by elemental analysis, <sup>1</sup>H-NMR, UV-Visible, FT-IR, TGA analysis and magnetic susceptibility measurements. The results from the above analytical techniques showed that the complexes are in an octahedral geometry. </span><span>The antimicrobial activity of the synthesized ligands and their metal complexes under study was carried out by using the agar well diffusion method.</span><strong><span> </span></strong><span>The ligand and complex interactions for biological targets were predicted using molecular docking and high binding affinities.</span></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_15695249 |
| institution | Zenodo |
| language | |
| publishDate | 2023 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | Synthesis, Physicochemical Characterization And Biological Activities Of Dapsone Derived Schiff Base Ligand And Their Co(II) Complexes Gaikwad, Mrs. Kundalkesha Dharmentra diphenylsulphone; Ligand; Co (II) complex; biological activity <p><strong><span>Abstract:</span></strong><span> </span></p> <p><span>This work presents the synthesis and characterization of five <a name="_Hlk115000827"></a>diphenylsulphone (Dapsone) derived Schiff base ligands (L<sub>1</sub>- L<sub>5</sub>). Using the aforementioned ligands, Co (II) complexes were synthesized in 1:1 stoichiometric ratio. The synthesized Schiff base and their complexes were characterized by elemental analysis, <sup>1</sup>H-NMR, UV-Visible, FT-IR, TGA analysis and magnetic susceptibility measurements. The results from the above analytical techniques showed that the complexes are in an octahedral geometry. </span><span>The antimicrobial activity of the synthesized ligands and their metal complexes under study was carried out by using the agar well diffusion method.</span><strong><span> </span></strong><span>The ligand and complex interactions for biological targets were predicted using molecular docking and high binding affinities.</span></p> |
| title | Synthesis, Physicochemical Characterization And Biological Activities Of Dapsone Derived Schiff Base Ligand And Their Co(II) Complexes |
| topic | diphenylsulphone; Ligand; Co (II) complex; biological activity |
| url | https://doi.org/10.5281/zenodo.15695249 |