Experimental Evalution of Antidiabetic Activity of Swertia Chirata – Aqueous Extract

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Auteurs principaux: Suman Chandel, Chandrika Ahirwal
Format: Recurso digital
Publié: Zenodo 2025
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author Suman Chandel
Chandrika Ahirwal
author_facet Suman Chandel
Chandrika Ahirwal
contents <p>Diabetes is a metabolic desease and plant derived products are used to combate this deadly disease. Leaves of Swertia chirata (Faimily; Gentianaceae) is one of the illustrious leafy vetetable that is used for this purpose traditionally. It has been used against diabetes for a long while. The alcoholic extract of Swertia chirayita extract was treated for its biochemical and pathomorphological effect in streptozotocin induced diabeted in rats. To study the antidiabetic activity of aqueous extract of Swertia chirata in streptozotocin induced diabetes in albino rats. To campare the antidiabetic activity of Swertia chirata extracts with that of standard drug glibenclamide used in treatment of type2 diabetes mellitus. In this present study 24 male albino wistar rats divided into 4 groups with 6 animals were taken. One groupas control was given normal salin for 21days daily. Other3 groups were induced diabetes. Standard and test groups were fed with glibenclamide (0.5mg/kg) and aqueous extract (200mg/kg) daily respectively. The result were analysed with ANOVA (Analysis of variance) and comparison with standard, test and control groups done by post hoc tukeys test. p>0.001 was considered highly significant.</p>
format Recurso digital
id zenodo_https___doi_org_10_5281_zenodo_15747087
institution Zenodo
language
publishDate 2025
publisher Zenodo
record_format zenodo
spellingShingle Experimental Evalution of Antidiabetic Activity of Swertia Chirata – Aqueous Extract
Suman Chandel
Chandrika Ahirwal
<p>Diabetes is a metabolic desease and plant derived products are used to combate this deadly disease. Leaves of Swertia chirata (Faimily; Gentianaceae) is one of the illustrious leafy vetetable that is used for this purpose traditionally. It has been used against diabetes for a long while. The alcoholic extract of Swertia chirayita extract was treated for its biochemical and pathomorphological effect in streptozotocin induced diabeted in rats. To study the antidiabetic activity of aqueous extract of Swertia chirata in streptozotocin induced diabetes in albino rats. To campare the antidiabetic activity of Swertia chirata extracts with that of standard drug glibenclamide used in treatment of type2 diabetes mellitus. In this present study 24 male albino wistar rats divided into 4 groups with 6 animals were taken. One groupas control was given normal salin for 21days daily. Other3 groups were induced diabetes. Standard and test groups were fed with glibenclamide (0.5mg/kg) and aqueous extract (200mg/kg) daily respectively. The result were analysed with ANOVA (Analysis of variance) and comparison with standard, test and control groups done by post hoc tukeys test. p>0.001 was considered highly significant.</p>
title Experimental Evalution of Antidiabetic Activity of Swertia Chirata – Aqueous Extract
url https://doi.org/10.5281/zenodo.15747087