A Case of Anaphylaxis After Ibuprofen Use

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Main Authors: Tasli Salman, Sevval, Yapar Gumus, Ceren, Ozer, Murat
Format: Recurso digital
Published: Zenodo 2025
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author Tasli Salman, Sevval
Yapar Gumus, Ceren
Ozer, Murat
author_facet Tasli Salman, Sevval
Yapar Gumus, Ceren
Ozer, Murat
contents <p>Introduction: Anaphylaxis is a potentially life-threatening hypersensitivity reaction that may be triggered by immunoglobulin E (IgE) or non-IgE mediated mechanisms. Non-steroidal anti-inflammatory drugs (NSAIDs) are known to provoke anaphylaxis via direct mast cell activation, even in previously undiagnosed patients.</p> <p>Case Presentation: We report a case of a 17-year-old adolescent male who developed anaphylaxis following ibuprofen ingestion. The clinical diagnosis was supported despite a normal serum tryptase level, and the patient was treated successfully with intramuscular adrenaline.</p> <p>Conclusion: This case emphasizes the importance of early recognition, prompt treatment, and long-term individualized management in adolescents.</p>
format Recurso digital
id zenodo_https___doi_org_10_5281_zenodo_15802065
institution Zenodo
language
publishDate 2025
publisher Zenodo
record_format zenodo
spellingShingle A Case of Anaphylaxis After Ibuprofen Use
Tasli Salman, Sevval
Yapar Gumus, Ceren
Ozer, Murat
Adolescent
anaphylaxis
epinephrine
ibuprofen
NSAIDs
<p>Introduction: Anaphylaxis is a potentially life-threatening hypersensitivity reaction that may be triggered by immunoglobulin E (IgE) or non-IgE mediated mechanisms. Non-steroidal anti-inflammatory drugs (NSAIDs) are known to provoke anaphylaxis via direct mast cell activation, even in previously undiagnosed patients.</p> <p>Case Presentation: We report a case of a 17-year-old adolescent male who developed anaphylaxis following ibuprofen ingestion. The clinical diagnosis was supported despite a normal serum tryptase level, and the patient was treated successfully with intramuscular adrenaline.</p> <p>Conclusion: This case emphasizes the importance of early recognition, prompt treatment, and long-term individualized management in adolescents.</p>
title A Case of Anaphylaxis After Ibuprofen Use
topic Adolescent
anaphylaxis
epinephrine
ibuprofen
NSAIDs
url https://doi.org/10.5281/zenodo.15802065