| _version_ | 1866902273466040320 |
|---|---|
| author | Cancel Asencio, Héctor |
| author_facet | Cancel Asencio, Héctor |
| contents | <p>Originally published online at <a href="https://arbonahealthhub.com/2024/03/28/science-behind-alzheimers-treatments-a-comprehensive-yet-simplified-exploration/">https://arbonahealthhub.com/2024/03/28/science-behind-alzheimers-treatments-a-comprehensive-yet-simplified-exploration/</a></p> <p>This article by Héctor Cancel Asencio offers an accessible yet informative overview of current pharmacological treatments for Alzheimer’s disease (AD), focusing on both symptom-relieving and disease-modifying therapies. It highlights FDA-approved medications such as acetylcholinesterase inhibitors (Donepezil, Galantamine, Rivastigmine), which aim to increase acetylcholine levels, and monoclonal antibodies like Aducanumab and Lecanemab that target amyloid-beta plaques. The article also introduces emerging research directions, including the inhibition of Fyn Kinase to reduce tau protein accumulation, a hallmark of tauopathies. It notes recent developments like the discontinuation of Aducanumab and shifting research priorities toward inflammation and alternative targets beyond amyloid and tau. While the article emphasizes that no cure currently exists, it underscores the critical role of ongoing research and multidisciplinary strategies in improving patient outcomes and deepening our understanding of AD.</p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_15838602 |
| institution | Zenodo |
| language | eng |
| publishDate | 2024 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | Science Behind Alzheimer's Treatments: A Comprehensive Yet Simplified Exploration Cancel Asencio, Héctor Alzheimer Disease <p>Originally published online at <a href="https://arbonahealthhub.com/2024/03/28/science-behind-alzheimers-treatments-a-comprehensive-yet-simplified-exploration/">https://arbonahealthhub.com/2024/03/28/science-behind-alzheimers-treatments-a-comprehensive-yet-simplified-exploration/</a></p> <p>This article by Héctor Cancel Asencio offers an accessible yet informative overview of current pharmacological treatments for Alzheimer’s disease (AD), focusing on both symptom-relieving and disease-modifying therapies. It highlights FDA-approved medications such as acetylcholinesterase inhibitors (Donepezil, Galantamine, Rivastigmine), which aim to increase acetylcholine levels, and monoclonal antibodies like Aducanumab and Lecanemab that target amyloid-beta plaques. The article also introduces emerging research directions, including the inhibition of Fyn Kinase to reduce tau protein accumulation, a hallmark of tauopathies. It notes recent developments like the discontinuation of Aducanumab and shifting research priorities toward inflammation and alternative targets beyond amyloid and tau. While the article emphasizes that no cure currently exists, it underscores the critical role of ongoing research and multidisciplinary strategies in improving patient outcomes and deepening our understanding of AD.</p> |
| title | Science Behind Alzheimer's Treatments: A Comprehensive Yet Simplified Exploration |
| topic | Alzheimer Disease |
| url | https://doi.org/10.5281/zenodo.15838602 |