Advances in Perioperative Anesthesia Protocols for Optimizing Glycemic Control in Patients with Type 2 Diabetes: A Systematic Review
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2025
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| author | Dr. Sahar Hameed Rasheed Alani1, Dr. Yasmin Ali Alissa2, Dr. Hany Fawzi W. Greiss3, Dr. Osama Sami Maki Al Ani4 |
| author_facet | Dr. Sahar Hameed Rasheed Alani1, Dr. Yasmin Ali Alissa2, Dr. Hany Fawzi W. Greiss3, Dr. Osama Sami Maki Al Ani4 |
| contents | <p><strong><u><span>ABSTRACT</span></u></strong><span>:</span></p> <p><span>Patients with type 2 diabetes mellitus (T2DM) undergoing surgery face<span> </span>increased risks of perioperative complications due to glycemic variability.<span> </span>Recent advancements in anesthesia protocols, including continuous glucose monitoring (CGM), individualized insulin delivery, and novel pharmacological agents, have aimed to optimize glycemic control during the perioperative period.<span> </span>This systematic review synthesizes evidence from studies published between<span> </span>2015<span> </span>and<span> </span>2025,<span> </span>evaluating<span> </span>the<span> </span>efficacy,<span> </span>safety,<span> </span>and<span> </span>feasibility<span> </span>of these protocols in T2DM patients.<span> </span>We identified 32 studies through PubMed, Embase, and Cochrane Library searches, focusing on protocols integrating<span> </span>CGM,<span> </span>insulin<span> </span>infusion<span> </span>algorithms, and<span> </span>sodium glucose<span> </span>cotransporter-2<span> </span>(SGLT2) inhibitors. Findings indicate that CGM-based protocols improve time in target<span> </span>glucose<span> </span>range<span> </span>(80–180<span> </span>mg/dL)<span> </span>by<span> </span>15–25%<span> </span>compared<span> </span>to<span> </span>standard<span> </span>care,</span><span> <span>with<span> </span>reduced<span> </span>rates<span> </span>of<span> </span>postoperative<span> </span>complications.<span> </span>However,<span> </span>challenges<span> </span>such as cost training requirements, and protocol standardization persist.<span> </span>This review highlights the potential of technology driven anesthesia protocols to enhance surgical outcomes in T2DM patients and identifies gaps for future <span>research.</span></span></span></p> <p><strong><span> </span></strong></p> <p><strong><em><span>Keywords: Type<span> </span>2<span> </span>diabetes,<span> </span>perioperative<span> </span>anesthesia,<span> </span>glycemic<span> </span>control,<span> </span>continuous glucose monitoring, insulin therapy, surgical outcomes</span></em></strong></p> <p><strong><em><span> </span></em></strong></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_15881550 |
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| publishDate | 2025 |
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| spellingShingle | Advances in Perioperative Anesthesia Protocols for Optimizing Glycemic Control in Patients with Type 2 Diabetes: A Systematic Review Dr. Sahar Hameed Rasheed Alani1, Dr. Yasmin Ali Alissa2, Dr. Hany Fawzi W. Greiss3, Dr. Osama Sami Maki Al Ani4 <p><strong><u><span>ABSTRACT</span></u></strong><span>:</span></p> <p><span>Patients with type 2 diabetes mellitus (T2DM) undergoing surgery face<span> </span>increased risks of perioperative complications due to glycemic variability.<span> </span>Recent advancements in anesthesia protocols, including continuous glucose monitoring (CGM), individualized insulin delivery, and novel pharmacological agents, have aimed to optimize glycemic control during the perioperative period.<span> </span>This systematic review synthesizes evidence from studies published between<span> </span>2015<span> </span>and<span> </span>2025,<span> </span>evaluating<span> </span>the<span> </span>efficacy,<span> </span>safety,<span> </span>and<span> </span>feasibility<span> </span>of these protocols in T2DM patients.<span> </span>We identified 32 studies through PubMed, Embase, and Cochrane Library searches, focusing on protocols integrating<span> </span>CGM,<span> </span>insulin<span> </span>infusion<span> </span>algorithms, and<span> </span>sodium glucose<span> </span>cotransporter-2<span> </span>(SGLT2) inhibitors. Findings indicate that CGM-based protocols improve time in target<span> </span>glucose<span> </span>range<span> </span>(80–180<span> </span>mg/dL)<span> </span>by<span> </span>15–25%<span> </span>compared<span> </span>to<span> </span>standard<span> </span>care,</span><span> <span>with<span> </span>reduced<span> </span>rates<span> </span>of<span> </span>postoperative<span> </span>complications.<span> </span>However,<span> </span>challenges<span> </span>such as cost training requirements, and protocol standardization persist.<span> </span>This review highlights the potential of technology driven anesthesia protocols to enhance surgical outcomes in T2DM patients and identifies gaps for future <span>research.</span></span></span></p> <p><strong><span> </span></strong></p> <p><strong><em><span>Keywords: Type<span> </span>2<span> </span>diabetes,<span> </span>perioperative<span> </span>anesthesia,<span> </span>glycemic<span> </span>control,<span> </span>continuous glucose monitoring, insulin therapy, surgical outcomes</span></em></strong></p> <p><strong><em><span> </span></em></strong></p> |
| title | Advances in Perioperative Anesthesia Protocols for Optimizing Glycemic Control in Patients with Type 2 Diabetes: A Systematic Review |
| url | https://doi.org/10.5281/zenodo.15881550 |