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2025
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| Online-Zugang: | https://doi.org/10.5281/zenodo.16312269 |
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| _version_ | 1866901566121836544 |
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| author | Chiaradia, Ilaria |
| author_facet | Chiaradia, Ilaria |
| contents | <p>Raw images (.tif), ROI files (.roi), and morphological analysis outputs (.jpg) of day 18 input organoids tested for their morphological features against reference dataset. + .csv file with the results of the morphological analysis of reference+input organoids with and without organoid size descriptors (.csv). + pca data of reference+input organoids (.xlsx)<br>Input organoids we tested on the reference pool are generated according to the following protocols: CondCO CondSWbCOEFC, CondSWbCO, CondCOnoMG, CondbCOC.</p> <p>CondCO – cerebral organoids made according to an optimized protocol with a proprietary media but lacking patterning molecules; CondCOnoMG – CO without exposure to Matrigel; CondSWbCO – guided cerebral organoid treated with SMAD WNT (TGFß and WNT) inhibitors; CondSWbCOEFC – guided cerebral organoid treated with SMAD WNT (TGFß and WNT) inhibitors plus treatment with epidermal growth factor (EGF), fibroblast growth factor (FGF), and GSK3 Inhibitor/WNT Activator (CHIR-99021) during neuroepithelial expansion; CondbCOC – unguided cerebral organoid in basal medium plus treatment with GSK3 Inhibitor/WNT Activator (CHIR-99021) during neuroepithelial expansion.<br>B=batch number</p> <p>For further details on the protocol steps refer to Chiaradia, Imaz-Rosshandler et al., 2023<sup>2</sup>.</p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_16312269 |
| institution | Zenodo |
| language | |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | Raw images (.tif), ROI files (.roi), and morphological analysis outputs (.jpg) of day 18 input organoids tested for their morphological features against reference dataset. + .csv file with the results of the morphological analysis of reference+input organoids with and without organoid size descriptors (.csv). + pca data of reference and input organoids (.xlsx) Chiaradia, Ilaria <p>Raw images (.tif), ROI files (.roi), and morphological analysis outputs (.jpg) of day 18 input organoids tested for their morphological features against reference dataset. + .csv file with the results of the morphological analysis of reference+input organoids with and without organoid size descriptors (.csv). + pca data of reference+input organoids (.xlsx)<br>Input organoids we tested on the reference pool are generated according to the following protocols: CondCO CondSWbCOEFC, CondSWbCO, CondCOnoMG, CondbCOC.</p> <p>CondCO – cerebral organoids made according to an optimized protocol with a proprietary media but lacking patterning molecules; CondCOnoMG – CO without exposure to Matrigel; CondSWbCO – guided cerebral organoid treated with SMAD WNT (TGFß and WNT) inhibitors; CondSWbCOEFC – guided cerebral organoid treated with SMAD WNT (TGFß and WNT) inhibitors plus treatment with epidermal growth factor (EGF), fibroblast growth factor (FGF), and GSK3 Inhibitor/WNT Activator (CHIR-99021) during neuroepithelial expansion; CondbCOC – unguided cerebral organoid in basal medium plus treatment with GSK3 Inhibitor/WNT Activator (CHIR-99021) during neuroepithelial expansion.<br>B=batch number</p> <p>For further details on the protocol steps refer to Chiaradia, Imaz-Rosshandler et al., 2023<sup>2</sup>.</p> |
| title | Raw images (.tif), ROI files (.roi), and morphological analysis outputs (.jpg) of day 18 input organoids tested for their morphological features against reference dataset. + .csv file with the results of the morphological analysis of reference+input organoids with and without organoid size descriptors (.csv). + pca data of reference and input organoids (.xlsx) |
| url | https://doi.org/10.5281/zenodo.16312269 |