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| Natura: | Recurso digital |
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Zenodo
2025
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| Accesso online: | https://doi.org/10.5281/zenodo.16452472 |
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| _version_ | 1866902264331894784 |
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| author | Mamoor, Shahan |
| author_facet | Mamoor, Shahan |
| contents | <p>Membrane expression of receptors in circulating tumor cells remains incompletely defined. We identified enrichment of SMIM38 when studying membrane expression of receptors in circulating tumor cells in humans with metastatic breast cancer. SMIM38 function was studied at the interaction level using proteomics, identifying ETDA and ETDB as protein-protein interaction partners. Both ETDA and ETDB were also transcriptionally active in the circulating tumor cell. SMIM38 functions with ETDA and ETDB in circulation during metastasis in humans with cancer. </p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_16452472 |
| institution | Zenodo |
| language | |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | The integral membrane protein SMIM38 is transcriptionally activated in circulating tumor cells in human breast cancer in conjunction with two SMIM38-interacting proteins of undefined function, ETDA and ETDB. Mamoor, Shahan <p>Membrane expression of receptors in circulating tumor cells remains incompletely defined. We identified enrichment of SMIM38 when studying membrane expression of receptors in circulating tumor cells in humans with metastatic breast cancer. SMIM38 function was studied at the interaction level using proteomics, identifying ETDA and ETDB as protein-protein interaction partners. Both ETDA and ETDB were also transcriptionally active in the circulating tumor cell. SMIM38 functions with ETDA and ETDB in circulation during metastasis in humans with cancer. </p> |
| title | The integral membrane protein SMIM38 is transcriptionally activated in circulating tumor cells in human breast cancer in conjunction with two SMIM38-interacting proteins of undefined function, ETDA and ETDB. |
| url | https://doi.org/10.5281/zenodo.16452472 |