KirklandLab/CRISPR-ScreenAnalysis: v1.0.0

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Auteur principal: Kevin Boyd
Format: Recurso digital
Publié: Zenodo 2025
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author Kevin Boyd
author_facet Kevin Boyd
contents <p>CRISPR-ScreenAnalysis is an automated Snakemake workflow for pooled CRISPR screen analysis using MAGeCK, supporting both single-end and paired-end data. The pipeline performs FASTQ quality control, sgRNA counting with a user-provided library, use of an automated or custom design matrix generation, and gene-level β score estimation via MAGeCK MLE. Designed for reproducibility and scalability in Slurm-managed HPC environments.</p>
format Recurso digital
id zenodo_https___doi_org_10_5281_zenodo_16809384
institution Zenodo
language
publishDate 2025
publisher Zenodo
record_format zenodo
spellingShingle KirklandLab/CRISPR-ScreenAnalysis: v1.0.0
Kevin Boyd
<p>CRISPR-ScreenAnalysis is an automated Snakemake workflow for pooled CRISPR screen analysis using MAGeCK, supporting both single-end and paired-end data. The pipeline performs FASTQ quality control, sgRNA counting with a user-provided library, use of an automated or custom design matrix generation, and gene-level β score estimation via MAGeCK MLE. Designed for reproducibility and scalability in Slurm-managed HPC environments.</p>
title KirklandLab/CRISPR-ScreenAnalysis: v1.0.0
url https://doi.org/10.5281/zenodo.16809384