SARS-CoV-2 Spike Mutation Co-occurrence Network - Segment 3: Genomic Surveillance of Co-evolving Mutations in a Global Dataset

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Autore principale: Tahir, Bhatti
Natura: Recurso digital
Lingua:inglese
Pubblicazione: Zenodo 2025
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author Tahir, Bhatti
author_facet Tahir, Bhatti
contents <p>=== SARS-CoV-2 SPIKE GENE CO-OCCURRENCE PROJECT ===<br>Chunk files processed: 40 (cooccur_chunk_000111.tsv → cooccur_chunk_000150.tsv)<br>Date (UTC): 2025-08-27T15:12:27Z</p> <p>Scope of Study:<br>  • Sequences analyzed (approx.): 5,000,000<br>  • Mutation events recorded (approx.): 100,000,000<br>  • Pairwise co-mutation tests performed: 3,800,000</p> <p>Findings from this batch:<br>  • Mutation pair records analyzed: 40,000<br>  • Total co-occurrence observations: 1,213,785,275<br>  • Additional sequences beyond top100 lists: 1,209,785,275<br>  • Total accession entries (with duplicates): 4,000,000<br>  • Unique accessions detected: 21,460<br>  • Unique countries represented: 89</p> <p>Interpretation:<br>  This dataset is part of one of the largest systematic analyses of SARS-CoV-2 spike co-mutations.<br>  The scale captures global viral evolution at high resolution, providing funders and policy-makers<br>  with quantitative evidence of recurrent mutation networks, their spread across regions, and their<br>  potential impact on immunity and vaccines.</p> <p> </p>
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spellingShingle SARS-CoV-2 Spike Mutation Co-occurrence Network - Segment 3: Genomic Surveillance of Co-evolving Mutations in a Global Dataset
Tahir, Bhatti
SARS-CoV-2
mutations
Spike
<p>=== SARS-CoV-2 SPIKE GENE CO-OCCURRENCE PROJECT ===<br>Chunk files processed: 40 (cooccur_chunk_000111.tsv → cooccur_chunk_000150.tsv)<br>Date (UTC): 2025-08-27T15:12:27Z</p> <p>Scope of Study:<br>  • Sequences analyzed (approx.): 5,000,000<br>  • Mutation events recorded (approx.): 100,000,000<br>  • Pairwise co-mutation tests performed: 3,800,000</p> <p>Findings from this batch:<br>  • Mutation pair records analyzed: 40,000<br>  • Total co-occurrence observations: 1,213,785,275<br>  • Additional sequences beyond top100 lists: 1,209,785,275<br>  • Total accession entries (with duplicates): 4,000,000<br>  • Unique accessions detected: 21,460<br>  • Unique countries represented: 89</p> <p>Interpretation:<br>  This dataset is part of one of the largest systematic analyses of SARS-CoV-2 spike co-mutations.<br>  The scale captures global viral evolution at high resolution, providing funders and policy-makers<br>  with quantitative evidence of recurrent mutation networks, their spread across regions, and their<br>  potential impact on immunity and vaccines.</p> <p> </p>
title SARS-CoV-2 Spike Mutation Co-occurrence Network - Segment 3: Genomic Surveillance of Co-evolving Mutations in a Global Dataset
topic SARS-CoV-2
mutations
Spike
url https://doi.org/10.5281/zenodo.16966614