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| Format: | Recurso digital |
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Zenodo
2025
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| Online-Zugang: | https://doi.org/10.5281/zenodo.16988106 |
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Inhaltsangabe:
- <p><span lang="EN-GB">This paper aims to know the Connection between Fatty Liver Disease and Abnormal Liver Function in Iraq, where fatty liver disease is an emerging public health dilemma defined by excess hepatic fat accumulation not resulting from appreciable alcohol consumption. This cross-sectional study assessed 104 patients with a diagnosis of fatty liver disease (FLD) and abnormal liver function over one year in Iraq, to clarify interrelations between clinical, demographic, and risk factors and the severity of liver injury where<span> </span>Patients were subjected to extensive liver function assays, ultrasound grading of steatosis, and fibrosis evaluation by FIB-4 and NAFLD scoring systems while the<span> </span>Outcomes demonstrated a preponderance of middle-aged, overweight men with a high percentage having non-alcoholic steatohepatitis (NASH). Raised liver enzymes (ALT, AST) were significantly associated with increased body mass index (BMI), outlining obesity's central role in the disease process, and through<span> </span>Logistic regression disclosed BMI, smoking, alcohol use, diabetes, and older age as influential independent risk factors for FLD with<span> </span>Follow-up results demonstrated that lifestyle changes led to improvement or stabilization in the majority of patients, but a minority demonstrated disease progression, emphasizing the necessity for careful monitoring. Although liver function tests are valuable indicators of hepatocellular damage, they are still inadequate to adequately differentiate disease severity adequately at conclusion. This work supports the multifactorial cause of FLD and the imperative of early detection, management of risk factors, and individualized intervention plans to prevent disease progression and liver damage</span><span lang="EN-US">.</span></p>